恶性肿瘤术后合并不孕症患者经体外受精-胚胎移植治疗获妊娠3例报道并文献复习  

Successful pregnancy in women with infertility following surgeries for gynecological malignancies: report of 3 cases and literature review

作　　者：王楠[1] 陈薪[1] 叶德盛[1] 许丽娟[1] 田小龙[1] 陶婷[1] 陈士岭[1] 

机构地区：[1]南方医科大学南方医院妇产科生殖医学中心,广东广州510515

出　　处：《南方医科大学学报》2015年第6期838-843,共6页Journal of Southern Medical University

基　　金：国家自然科学基金(81170574)~~

摘　　要：探讨恶性肿瘤术后合并不孕症患者经体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)治疗的可行性及治疗结局。3例妇科恶性肿瘤术后合并不孕症患者行超促排卵周期IVF-ET,治疗后3例患者均成功获得临床妊娠,无肿瘤复发。由于妇科恶性肿瘤治疗可对女性患者的卵巢储备功能造成严重影响,因此对于恶性肿瘤术后合并不孕症患者,应采取积极助孕治疗。We report 3 cases of successful pregnancies in women with a history of surgeries for gynecological malignancies and postoperative infertility, achieved by in vitro fertilization- embryo transfer（IVF- ET） with controlled ovarian hyperstimulation.All the 3 patients had clinical pregnancies without cancer recurrence. In such cancer survivors with infertility, the ovarian reserve is severely impaired by cancer therapies and assisted reproductive techniques should be the primary option.

关 键 词：生育力 恶性肿瘤 生殖技术 辅助 不孕症 卵巢储备功能 卵巢低反应 

分 类 号：R714.8[医药卫生—妇产科学]