Controlled drug delivery systems based on calixarenes  

作　　者：Yue Zhou Hui Li Ying-Wei Yang 

机构地区：[1]State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Jilin University

出　　处：《Chinese Chemical Letters》2015年第7期825-828,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China (Nos. 21272093 and 51473061);the Fundamental Research Funds for the Central Universities (No. JCKY-QKJC05) for financial support

摘　　要：In recent years, cancer has become the number two cause of death around the world, and scientists have exploited various treatment maps. Calixarenes, with diversified features, have been widely applied into drug delivery systems, which can respond to multi-stimuli and exhibit excellent performance. In this mini-review, we summarize the recent advances on controlled drug delivery systems based on calixarenes, in the form of inclusion complexes, amphiphilic self-assembly nanocarriers including micelles, hydrogels, vesicles and liposomes, and supramolecular nanovalves on mesoporous silica nanomaterials.In recent years, cancer has become the number two cause of death around the world, and scientists have exploited various treatment maps. Calixarenes, with diversified features, have been widely applied into drug delivery systems, which can respond to multi-stimuli and exhibit excellent performance. In this mini-review, we summarize the recent advances on controlled drug delivery systems based on calixarenes, in the form of inclusion complexes, amphiphilic self-assembly nanocarriers including micelles, hydrogels, vesicles and liposomes, and supramolecular nanovalves on mesoporous silica nanomaterials.

关 键 词：Drug delivery systems Calixarenes Assembly Nanocarriers 

分 类 号：TQ460.1[化学工程—制药化工]