益气活血膏方与补阳还五汤颗粒对气虚血瘀证患者血凝影响的比较性研究  

The Efficacy of YiQiHuoXue Herbal Extracta and BuYang HanWu Granules on Blood Coagulation Index in Patients with Qi Deficiency and Blood Stasis Syndrome: a Comparative Study

作　　者：施怡[1] 王冬梅[1] 姚新颖 陈娟[1] 刘爱琪[1] 孙秋玲[1] 董青[1] 李靖[1] 韦杰[1] 陈信义[1] 

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《世界中医药》2015年第6期852-855,共4页World Chinese Medicine

基　　金：北京中医药大学自主创新中青年教师课题资助项目(编号:JYBZZ-JS058)

摘　　要：目的:通过检测血凝指标,比较益气活血膏方与补阳还五汤颗粒治疗气虚血瘀证临床有效性。方法:采用前瞻性随机对照研究方法,将60名气虚血瘀证患者随机分为益气活血膏方(治疗)、补阳还五汤颗粒(对照)2组。对照组按照补阳还五汤剂量配制颗粒,1袋/次,2次/d;治疗组服用与对照组相等量的膏方,疗程28 d。分别于治疗前后检测血凝指标变化,并统计分析。结果:治疗28 d后,治疗组PT、APTT、TT、FIB均有不同程度的改善,与对照组比较,具有统计学意义(P<0.05);2组治疗后减治疗前差值的平均值比较,具有统计学意义(P<0.05)。结论:益气活血膏方能更好的改善气虚血瘀证患者血凝指标,且具有良好的安全型。Objective： To compare the efficacy of Yi Qi Huo Xue herbal extracta（ treatment group） with Bu Yang Han Wu granules（ control group） by blood coagulation index. Methods： This prospective randomized controlled study enrolled 30 Qi Deficiency and Blood Stasis Syndrome（ QDBSS） patients in the treatment group which was treated with agreement herbal extract,and enrolled 30 QDBSS patients in the control group which was treated with Bu Yang Han Wu granules. Used blood coagulation index to assess efficacy of two group in 28 th day. Results： After treating with Yi Qi Huo Xue herbal extracta,PT,APTT and TT prolonged,while FIB decreased. And the blood coagulation indexes of treatment group improved dramatically than control group（ P〈0. 05）. Conclusion： To compare with control group,Yi Qi Huo Xue herbal extract had better effects on improving blood coagulation index. Yi QiHuo Xue herbal extracta is safe to use in clinical practice.

关 键 词：膏方 气虚血瘀证 血凝指标 

分 类 号：R259.414[医药卫生—中西医结合]