不同种类刺激声对国人青年正常人群气导声刺激诱发的颈肌前庭诱发肌源性电位的影响  

Cervical vestibular evoked myogenic potential elicited by different types air conducted sounds among normal young Chinese people

作　　者：杨引通[1,2,3] 张青[1,2] 张睿[1,2] 陈彦飞[1,2] 吴彩芹[1,2] 寇小会 孔德敏[1,2] 井晓红[1,2] 许珉[1,2] 

机构地区：[1]西安交通大学医学院第二附属医院耳鼻咽喉头颈外科分院 [2]西安交通大学医学院第二附属医院耳病研究所,西安710004 [3]西安市第四医院耳鼻咽喉科,西安710004

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第13期1175-1178,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金(No:3013300/C170703);中央高校基本科研业务费专项资金(No:2012jdhz13);陕西省重大国际合作项目(No:2013KW-28);西安市科技攻关项目[No:SF1315(1)];西安交通大学医学院第二附属医院人才培养专项科研基金[No:RC(GG)201407]

摘　　要：目的：观察不同种类刺激声音对正常青年人群气导声刺激诱发的颈肌前庭诱发肌源性电位（ACScVEMP）各参数的影响。方法：选择20例（40耳）19-30岁的正常人为研究对象,男10例,女10例。刺激声分别采用500Hz Tone Burst、1 000Hz Tone Burst、Click进行双耳ACS-cVEMP检测,比较各种刺激声下ACScVEMP的引出率、阈值、P1潜伏期、N1潜伏期、P1-N1波间期、振幅及耳间对称性。结果：500Hz Tone Burst的ACS-cVEMP的引出率为97.5%（39/40）,1 000Hz Tone Burst的ACS-cVEMP的引出率为87.5%（35/40）,Click的引出率为67.5%（27/40）。500Hz Tone Burst与1 000Hz Tone Burst的引出率组间差异无统计学意义（P〉0.05）,500Hz Tone Burst和1 000Hz Tone Burst与Click的引出率组间有差异统计学意义（P〈0.05）,500Hz Tone Burst诱发的ACS-cVEMP的阈值、P1潜伏期、N1潜伏期、P1-N1波间期、振幅较其他2组参数组间对比差异有统计学意义（P〈0.05）,每一波形参数耳间对称性组间波形参数差异无统计学意义。结论：不同刺激声可以对国人正常青年人群ACS-cVEMP的引出率和各波形参数造成影响,500Hz Tone Burst是已知的ACScVEMP的最佳刺激声之一。Objective：To observe waveform difference among cervical vestibular evoked myogenic potentials（cVEMP）elicited with different types of air conducted sound in normal young Chinese subjects.Method：Twenty adult volunteers（40ears）were recruited as research subjects including 10 males and 10 females aged between 19 and 30.500 Hz Tone Burst,1000 Hz Tone Burst and Click were employed as stimulus for conventional air conducted sound-cVEMP（ACS-cVEMP）examinations in bilateral ears of each subject.The response rate,threshold,P1 latency,N1latency,P1-N1 latency interval,amplitude and inter-aural asymmetry were recorded and compared among groups.Result：The response rate was 97.5%in 500 Hz Tone Burst（39/40）,87.5%in 1 000 Hz Tone Burst（35/40）and 67.5%in Click（27/40）,There were no statistically significant difference between 500 Hz Tone Burst and 1000 Hz Tone Burst（P〉0.05）,but there were statistically significant difference between click and the other groups（P〈0.05）.We collected the waveform parameters（the threshold,P1 latency,N1latency,P1-N1 latency interval、amplitude）which had statistically significant difference between 500 Hz Tone Burst and the other groups（P〈0.05）.The inter-aural asymmetrys had no statistically significant differents among groups.Conclusion：The response rate and parameter could be affected by different types of air conducted sound in normal young Chinese subjects.500 Hz Tone Burst was the best stimulus of type what we have known.

关 键 词：前庭 颈肌前庭诱发肌源性电位 球囊 前庭下神经 诊断 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]