Maspin与Ki67在结外鼻型NK/T淋巴瘤中的表达与意义  

Expressions of Maspin and Ki67 in extranodal nasal type NK/T-cell lymphoma and the significance

作　　者：洪飞[1] 孙敬武[2] 李传应[3] 王晓秋[3] 陈晶晶[3] 顾萍[3] 

机构地区：[1]安徽医科大学合肥第三临床学院(合肥市第三人民医院耳鼻咽喉科),合肥230022 [2]安徽省立医院耳鼻咽喉-头颈外科 [3]安徽省立医院病理科

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第13期1184-1186,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:研究Maspin及Ki67在结外鼻型NK/T细胞淋巴瘤中的表达及意义。方法:采用免疫组织化学方法检测34例结外鼻型NK/T细胞淋巴瘤及11例慢性鼻窦炎组织中Maspin及Ki67的表达。结果:Maspin在结外鼻型NK/T细胞淋巴瘤中呈低表达,Ki67在结外鼻型NK/T细胞淋巴瘤中呈高表达,Maspin与Ki67的表达之间呈负相关。结论:联合检测Maspin及Ki67对结外鼻型NK/T细胞淋巴瘤的诊断有重要意义。Objective：To analyze the expression of Maspin and Ki67 in EN-NK/TCL and the significance.Method：The expressions of Maspin and Ki67 were detected by immunohistochemistry in 34 cases of EN-NK/TCL and 11 cases of chronic sinusitis.Result：Maspin was low expressed in EN-NK/TCL,Ki67 was highly expressed in EN-NK/TCL.Negative correlation was found between the expression of Maspin and Ki67 in EN-NK/TCL.Conclusion：The combined examination of Maspin and Ki67 has important significance in the diagnosis in EN-NK/TCL.

关 键 词：结外鼻型NK/T淋巴瘤 MASPIN KI67 免疫组织化学 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]