隐孢子虫病诊断和治疗研究进展  

Research advances in diagnosis and treatment of cryptosporidiosis

作　　者：刘彩霞[1] 赵继学[2] 尹继刚[1] 

机构地区：[1]人兽共患病研究教育部重点实验室吉林大学人兽共患病研究所,长春130062 [2]吉林大学第一医院儿外科,长春130021

出　　处：《传染病信息》2015年第3期133-136,148,共5页Infectious Disease Information

基　　金：国家自然科学基金(31072125;31272549)

摘　　要：隐孢子虫病对人和动物的健康造成威胁,尤其是儿童、免疫缺陷和断奶前的动物更为易感。目前治疗方法有限且无可用的疫苗。实验室诊断方法不仅能确诊感染病例,而且能够区分虫种和基因型,这些对于区分感染来源、确定传播方式和提供与暴发相关的流行病学证据至关重要。随着科技的发展,很多费时费力的诊断方法已被新的检测和分型技术所取代,并应用到临床和环境监测。本文对近年来隐孢子虫诊断和治疗的研究进展作一综述。The protozoan Cryptosporidium is a major public and animal health concern. Young children, immunocompromised people, and pre-weaning animals are especially vulnerable, but treatment options are limited and there is no vaccine. A laboratory diagnosis is required to confirm cases of cryptosporidiosis, and species and genotype determination is essential in distinguishing human from non-human sources, understanding transmission, and strengthening the epidemiological evidence for causative links in outbreaks.Many methods employed are laborious and time-consuming. Recent advances in diagnostic assays, can improve testing and facilitate genotyping to support clinical and environmental investigations. This review focuses on the research advances in diagnosis and treatment of cryptosporidiosis in recent years.

关 键 词：隐孢子虫属 隐孢子虫病 方法 诊断 

分 类 号：R382.3[医药卫生—医学寄生虫学] R394.3[医药卫生—基础医学]