氧化亚氮、哌替啶、间苯三酚对产程潜伏期延长倾向的效果研究  

Study on the effects of nitrous oxide,pethidine,and phloroglucinol on prolonged latency tendency in labor

作　　者：宁丰[1] 周霓[1] 韦小容 唐雨帆[1] 张东梅[1] 

机构地区：[1]广西壮族自治区南宁市妇幼保健院产科,530011

出　　处：《中国妇幼保健》2015年第21期3562-3565,共4页Maternal and Child Health Care of China

基　　金：广西壮族自治区南宁市科学研究与技术开发计划项目〔20123124〕

摘　　要：目的通过对在产程中有潜伏期延长倾向的产妇分别给予氧化亚氮吸入、哌替啶肌内注射、间苯三酚肌内注射,评价3种方法对产妇产程潜伏期延长倾向的处理效果。方法选择116例初产妇,分为氧化亚氮吸入组(40例)、哌替啶肌内注射组(39例)和间苯三酚肌内注射组(37例)。观察3组产妇经过处理后的进入活跃期时限、活跃期时限、总产程时间、分娩方式、胎儿窘迫发生率、产后出血量、羊水性状及新生儿Apgar评分。结果氧化亚氮吸入组、间苯三酚肌内注射组经处理后进入活跃期时限及剖宫产率均小于哌替啶肌内注射组,氧化亚氮吸入组总产程时间短于哌替啶肌内注射组和间苯三酚肌内注射组,差异均有统计学意义(P<0.05);3组活跃期时限、胎儿窘迫发生率、产后出血量、羊水性状及新生儿Apgar评分比较差异无统计学意义(P>0.05)。结论有产程潜伏期延长倾向时给予氧化亚氮吸入能缩短进入活跃期时限及总产程时间,提高自然分娩率,降低剖宫产率,不增加胎儿窘迫发生率,不影响羊水性状、产后出血量及新生儿Apgar评分。Objective To evaluate the effects of nitrous oxide, pethidine, and phloroglucinol on prolonged latency tendency in la- bor by treating the lying-in women with prolonged latency tendency in labor using nitrous oxide inhalation, intramuscular injection of pethi- dine, and intramuscular injection of phloroglucinol, respectively. Methods A total of 116 lying-in women were selected and divided into nitrous oxide inhalation group （40 cases）, pethidine group （39 cases）, and phloroglucinol group （37 cases） . After treatment, the time of entering active period, duration time of active period, the labor time, delivery modes, the incidence rates of fetal distress, the amounts of postpartum hemorrhage, the characteristics of amniotic fluid, and neonatal Apgar scores in the three groups were observed. Results After treatment, the time of entering active period and cesarean section rates in nitrous oxide inhalation group and phloroglucinol group were statis- tically significantly lower than those in pethidine group （P〈0.05） ; the labor time in nitrous oxide inhalation group and phloroglucinol group were statistically significantly shorter than that in pethidine group （ P〈0.05 ） ; there was no statistically significant difference in duration time of active period, the incidence rate of fetal distress, the amount of postpartum hemorrhage, the characteristics of amniotic fluid, and neonatal Apgar score among the three groups （ P〉0. 05 ） . Conclusion Nitrous oxide inhalation can shorten the time of entering active period and the labor time, improve spontaneous delivery rate, and reduce cesarean section rate of lying-in women with prolonged latency tendency in la- bor, and it does not increase the incidence rate of fetal distress, has no impact on the characteristics of amniotic fluid, the amount of postpar- tum hemorrhage, and neonatal Apgar score.

关 键 词：氧化亚氮 哌替啶 间苯三酚 潜伏期延长倾向 

分 类 号：R714.45[医药卫生—妇产科学]