正常妊娠妇女血脂和血糖水平与新生儿出生体质量的关系  

THE RELATIONSHIP OF BLOOD LIPID AND GLUCOSE WITH NEONATAL BIRTH WEIGHT IN NORMAL PREGNANT WOMEN

作　　者：张淑萍[1] 瓮占平[1] 王金会[1] 王言奎[2] 

机构地区：[1]青岛大学附属青岛市市立医院产科,山东青岛266071 [2]青岛大学附属医院妇科

出　　处：《青岛大学医学院学报》2015年第4期432-434,共3页Acta Academiae Medicinae Qingdao Universitatis

基　　金：中国营养学会妇幼营养分会资助课题

摘　　要：目的探讨新生儿出生体质量与正常妊娠妇女血脂和血糖水平的关系。方法选择在我院产检并分娩的正常单胎孕妇604例作为研究对象,根据新生儿出生体质量分为巨大儿组、正常体质量组,检测妊娠32~34周时孕妇血清总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）和血糖（FGB）水平,多元回归分析确定新生儿出生体质量的影响因素。结果巨大儿组孕妇TC、TG、LDL-C和FBG水平均高于正常体质量组,而HDL-C水平低于正常体质量组,差异有统计学意义（t=3.522~5.017,P〈0.05）;新生儿出生体质量与母体孕期体质量增长（β=0.325）、TC（β=0.128）、TG（β=0.406）和FGB（β=0.141）水平均呈明显正相关,差异有统计学意义（t=2.485~4.318,P〈0.05）。结论妊娠期孕妇血脂、血糖和体质量增长水平与新生儿出生体质量关系密切,应合理孕期孕妇体质量增长,降低巨大儿的发生率。Objective To explore the relationship of blood lipid and glucose with neonatal birth weight in normal pregnant women. Methods A total of 604single-birth pregnant women who received antenatal care and gave birth in our hospital were selected as the subjects of this study.They were divided into two group as macrosomia group,normal body weight group according to the neonatal body weight at birth.Total cholesterol（TC）,triglyceride（TG）,high density lipoprotein cholesterol（HDL-C）,low density lipoprotein cholesterol（LDL-C）and fasting blood glucose（FBG）were detected between 32-34 weeks of pregnacy.The influencing factors of neonatal birth weight were analyzed using multiple regression analysis. Results The levels of TC,TG,LDL-C and FBG of pregnant women in macrosomia group were significantly higher,and HDL-C was lower than that in the normal body weight group（t=3.522-5.017,P0.05）.The neonatal body weight at birth was positively correlated with matrix gestational weight gain（β=0.325）,TC（β=0.128）,TG（β=0.206）,and FBG（β=0.141）,（t=2.485-4.318,P0.05）.Conclusion The blood lipid and glucose of pregnant women and gestational weight gain are closely associated with the neonatal body weight at birth.The increase of body weight should be reasonably controlled in duration of pregnancy to decrease the occurence of macrosomia.

关 键 词：妊娠 血脂 血糖 出生体质量 

分 类 号：R714.7[医药卫生—妇产科学]