鼻咽癌放射治疗后放射性脑病120例临床分析  

Clinical analyses of radiation encephalopathy after radiotherapy of nasopharyngeal carcinoma: A Report of 120 Cases

作　　者：楼建军[1] 崔珍[1] 何斌[1] 殷红梅[1] 沈学明[1] 江浩[1] 

机构地区：[1]蚌埠医学院第一附属医院放疗科,安徽233004

出　　处：《齐齐哈尔医学院学报》2015年第17期2523-2524,共2页Journal of Qiqihar Medical University

基　　金：安徽省十二五临床医学重点专科建设基金(编号:01Z33)

摘　　要：目的探讨鼻咽癌放射治疗后放射性脑病的临床特点、治疗及预后。方法回顾性分析120例鼻咽癌在放射治疗后发生放射性脑病的临床资料。结果 120例发生放射性脑病病变部位:颞叶99例,双侧28例,单侧72例,脑桥20例。全组随访率100%,108例仍存活,12例死于放射性脑病。结论鼻咽癌放射性脑病与肿瘤分期、放射剂量及照射野设计有关。放射性脑病预后不佳,预防比治疗更重要。Objective To study the clinical characteristics,treatment and prognostic of patients with radiation ecephalopathy（ REP） after radiotherapy ofnasopharyngeal carcinoma（ NPC）. Methods Clinical datas of120 cases of NPC that occurred radiation encephalopathy after radiotherapy were analyzed retrospectively.Results 120 patients suffered from the radiation injury of brain. The lesions were located in temporal lobe in 99 patients,both sides of brain in 28 patients,single side in 72 patients,pons in 20 patients. All patients were revisited,108 patients still alive, 12 cases died of radiation encephalopathy. Conclusions Radiation ecephalopathy in NPC patients after radiotherapy are related to tumor staging and radiation dose and radiation field design. REP has worse prognosis,so the prevention should be more important than therapy.

关 键 词：鼻咽癌 放射治疗 放射性脑病 

分 类 号：R818.81[医药卫生—放射医学]