无氧条件下铜、镍和铁催化的芳基硫酚自偶联生成二芳基二硫醚  

Synthesis of diaryldisulfides via copper,nickel and iron-catalyzed homocoupling of aryl or benzyl thiols free of oxidants

作　　者：张斌[1] 张文鸿 郭海昌[1] 陈仁尔[1] 周其忠[1] 吴家守[1] 蒋华江[1] 

机构地区：[1]台州学院化学系,浙江台州318000 [2]浙江荣耀化工有限公司,浙江台州317000

出　　处：《浙江大学学报（理学版）》2015年第4期430-435,共6页Journal of Zhejiang University（Science Edition）

基　　金：国家自然科学基金资助项目(21172166;21402137);浙江省自然科学基金资助项目(LY14B020012);浙江省应用化学重点学科(台州学院)开放基金

摘　　要：苯硫酚或苯甲硫醇在CuI/Phen催化下,以Na2CO3为碱,乙二醇二甲醚为溶剂,在氮气保护下,回流搅拌可得二芳基二硫醚,收率为79%-99%;在Ni（PPh3）2Cl2催化下,以K2CO3为碱,得到的二芳基二硫醚的收率为77%-86%;在FeCl3/L-Proline催化下,以K2CO3为碱,甲醇为溶剂时,在氮气保护下,回流搅拌得到二芳基二硫醚,收率为86%-97%.为合成二芳基二硫醚提供了3种有效方法。Various symmetric diaryldisulfides were synthesized from commercially available aryl thiols catalyzed by CuI/Phen with Na2CO3 as a base in dimethoxyethane（DME）,and stirred and refluxed under the nitrogen atmosphere for high yields of 79%to 99%.In the presence of Ni（PPh3）2Cl2 with K2CO3 as a base under the nitrogen atmosphere,diaryldisulfides can be synthesized from aryl thiols in DME,whose yields are at the range of 77% to86%.Diaryldisulfides can also be synthesized from aryl thiols catalyzed by FeCl3/L-Proline with K2CO3 as a base in MeOH,and its yields are at the range of 86%to 97%.In this paper,we present three methods for the preparation of diaryldisulfides.

关 键 词：苯硫酚 CUI 镍 FECL3 二芳基二硫醚 

分 类 号：O621.3[理学—有机化学]