莫西沙星致不良反应3445例文献分析  

Literature Analysis of Moxifloxacin-induced Adverse Drugs Reactions in 3445 Cases

作　　者：赵东玲[1] 屈清慧[2,3] 李瑞林[1] 韩颖[1] 汪西萍[1] 

机构地区：[1]西安交通大学医院,西安710061 [2]西安交通大学药学院 [3]<西北药学杂志>编辑部,西安710061

出　　处：《中国药房》2015年第21期2913-2915,共3页China Pharmacy

摘　　要：目的:探讨莫西沙星致不良反应(ADR)的规律及特点,为临床合理用药提供参考。方法:检索2005-2014年我国期刊数据库报道的莫西沙星所致ADR病例,并就收集到的3 445例ADR相关信息进行统计和分析。结果:莫西沙星致ADR与性别有关,男性患者发生率较高,且多发生于中老年患者,用药10 min内可发生ADR,临床表现以变态反应、神经系统、消化系统损害较多。结论:临床应加强对莫西沙星ADR的监测,促进合理用药,尽量避免或减少ADR的发生。OBJECTIVE：To investigate the characteristics and regularity of moxifloxacin-induced adverse drug reaction（ADR）and provide reference for the rational clinical use of drugs. METHODS：Retrieved from CNKI（2005-2014）about the moxifloxacin-induced ADR,3 445 cases and the related ADR information were statistically analyzed. RESULTS：Moxifloxacin-induced ADR had a certain relationship with gender,and the male had a high incidence,especially the elderly patients. ADR could appear within10 min;the clinic features were allergic reaction,the nervous system and digestive system at most. CONCLUSIONS：Great importance should be attached to ADR monitoring and rational use of drug to reduce or avoid the occurrences of moxifloxacin-induced ADR.

关 键 词：莫西沙星 不良反应 文献分析 合理用药 

分 类 号：R978.1[医药卫生—药品]