基于电阻抗成像技术实时监测小猪肺出血模型的实验研究  

Experiment Study on EIT-Based Real-Time Monitoring of the Little Pig Pulmonary Hemorrhage Model

作　　者：代萌[1] 徐灿华[1] 杨滨[1] 夏军营[1] 刘本源[1] 刘锐岗[1] 史学涛[1] 尤富生[1] 付峰[1] 

机构地区：[1]第四军医大学生物医学工程系,陕西西安710032

出　　处：《中国医疗设备》2015年第7期19-21,共3页China Medical Devices

基　　金：军队课题(AWS14C006;CWS12J102);国家科技支撑计划课题(2012BAI20B02)

摘　　要：目的探讨基于电阻抗成像技术(EIT)实时监测小猪肺出血模型的可行性。方法以小猪肺出血模型为研究对象,采用EIT实时连续监测小猪肺出血过程中的电阻抗变化。结果当注血量每5 m L逐渐增加时,EIT图像的相应区域呈红色显示,并逐渐增强,EIT所显示的出血位置与CT所示的基本一致。定量分析结果表明,当注血量每5 m L逐渐增加时,图像上提示区域的阻抗、面积变化逐渐增大,EIT定量分析指标与注血量存在良好的相关性。结论 EIT技术能够实时有效地检测小猪肺出血引起的电阻抗变换,为临床研究奠定了基础。Objective To explore the feasibility of EIT-based（Electrical Impedance Tomography） realtime monitoring of the little pig pulmonary hemorrhage model. Methods As the objective of this study, electrical impedance changes of little pig pulmonary hemorrhage model was constantly and real-timely monitored with adoption of EIT. Results Gradual increase of each 5 m L of injected blood volume resulted in redness displayed in EIT images incorresponding areas and gradual enhancement. The hemorrhage locations revealed by EIT accorded with those displayed by CT. Quantitative analysis results indicated that gradual increase of each 5 m L of injected blood volume leaded togradually-enlarge delectrical impedance and area in the relevant locations in EIT images, which proved the relevance between EIT quantitative analysis indicators and the injected blood volume. Conclusion EIT could realtimely monitor the electrical impedance changes caused by pulmonary hemorrhage in little pigs in an effective way, which laid a solid foundation for clinical researches.

关 键 词：电阻抗成像技术 肺出血 动物实验 新生儿 阻抗信号 

分 类 号：R318[医药卫生—生物医学工程]