机构地区:[1]武汉大学人民医院,湖北武汉430060 [2]武汉市黄陂区人民医院儿科,湖北武汉430060 [3]武汉大学人民医院儿科,湖北武汉430060
出 处:《中国妇幼健康研究》2015年第3期488-490,共3页Chinese Journal of Woman and Child Health Research
摘 要:目的利用胎儿及新生儿心脏二维彩超图像,探讨围产期新生儿心室生长变化,定量分析胎儿期至出生后心室的形态变化。方法选取2012年3月至2013年8月于武汉市黄陂区人民医院行常规胎儿、新生儿超声检查且结果为正常者为研究对象,按胎龄或出生时间分为A(21~27w)、B(28~32w)、C(33~40w)、D(产后1w内)4组,各65例。A、B、C组行胎儿常规超声检查留取标准四腔心切面图像,D组新生儿行超声心动图检查留取标准四腔心切面图像。测量并记录各心室横径、长径、侧壁厚度、室间隔厚度及心室心尖角度,利用曲率半径测量软件测量左、右心室侧壁的最小曲率半径(LVCRm、RVCRm)及位置(LVCm%、RVCm%),测量室间隔最大曲率(IVSCm)、位置(IVSCm%),分析、比较各组间上述指标的差异。结果①从A组到D组,LVTD、LVLD及RVLD均呈递增趋势(LVTD、LVLD及RVLD的趋势x^2值分别为5.39、7.69和3.65,均P<0.05);D组的LVTD/RVTD显著大于A、B、C三组(t值分别为14.52、8.99和9.91,均P<0.05);②从A组到D组,LVLW、RVLW及IVS呈递增趋势,各组间差异有统计学意义(LVLW、RVLW及IVS的趋势x^2值分别为0.75、0.73和0.78,均P<0.05);③4组间LVAA比较无明显差异(F=1.10,P>0.05),D组的RVAA小于A、B、C组(t值分别为10.05、13.41和15.63,均P<0.05);④从A组到D组,LVCRm呈递增趋势(LVCRm的趋势x^2值为2.44,P<0.05)。结论胎儿期右心室占优势,随着胎儿心脏发育,出生后左、右心室比例相当。采用胎儿心脏超声检查技术及超声心动图可了解胎儿、新生儿心脏发育情况。Objective To investigate ventricular morphological changes with the growth of perinatal neonates and quantitatively analyze the morphological changes by echocardiography. Methods During the period of March 2012 to August 2013 fetus and newborns with normal results in routine ultrasound examination in People’s Hospital of Huangpi District of Wuhan were chosen and divided into group A (21-27 weeks), group B (28-32 weeks), group C (33-40 weeks) and group D (newborns within 7 days) according to fetus age and birth time. Each group had 65 cases. Fetus underwent fetal routine ultrasound examination and newborns underwent echocardiography examination. The standard four-chamber view images of fetus in group A, group B and group C and newborns in group D were remained. Left ventricular transverse diameter ( LVTD) and right ventricular transverse diameter ( RVLD) , left ventricular long diameter ( LVLD) , right ventricular long diameter ( RVLD ) , thickness of left ventricular lateral wall ( LVLW ) , thickness of right ventricular lateral wall ( RVLW) , thickness of interventricular septal ( IVS) , left ventricular apex angle ( LVAA) and right ventricular apex angle ( RVAA) were measured and recorded. The minimum left ventricular curvature radius ( LVCRm) , right ventricular curvature radius ( RVCRm) and their location ( LVCm%, RVCm%) , the maximum interventricular septum curvature ( IVSCm) and location ( ( IVSCm%) were measured with curvature radius measurement software. Results From group A to group D, LVTD, LVLD and RVLD showed a trend of increase (χ2 value was 5. 39, 7. 69 and 3. 65, respectively, all P〈0. 05). LVTD/RVTD in group D was greater than that of group A, group B and group C (t value was 14. 52, 8. 99 and 9. 91, respectively, all P〈0. 05). From group A to group D, LVLW, RVLW and IVS showed a trend of increase with significant difference (χ2 value was 0. 75, 0. 73 and 0. 78 respectively, all P〈0. 05). There was no o
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