幼年性黄色肉芽肿204例临床分析  

Analysis of 204 patients with juvenile xanthogranuloma

作　　者：李春晓[1] 顾艳[1] 凌波[1] 余红[1] 姚志荣[1] 

机构地区：[1]上海交通大学医学院附属新华医院皮肤科,上海200092

出　　处：《中国麻风皮肤病杂志》2015年第6期331-334,共4页China Journal of Leprosy and Skin Diseases

摘　　要：本文报道204例幼年性黄色肉芽肿患者,男女比例为1.65:1,约5.88%的患者出生时即有皮损,28.43%的患者于1岁以内发病,72.06%于5岁以内发病。单发皮损患者占73.53%。根据患者的皮损组织学特点可将其分为4种病理类型:早期幼年性黄色肉芽肿(24.51%)、经典型幼年性黄色肉芽肿(47.06%)、移行幼年性黄色肉芽肿(16.18%)和混合型幼年性黄色肉芽肿(n=25,12.25%)。免疫组化的皮损组织结果均为:CD68(+)、CD1a(-)及S-100(-)。治疗上主要采取手术切除。The clinical data of two hundred and four patients with juvenile xanthogranuloma （JXG） was analyzed. The ratio of male to female was 1. 65：1. 5. 88% of the patients presented with the lesions at birth. The lesions appeared before 1 year old in 28.43% of the patients and before 5 years old in 72.06% of the pa-tients. 73.53% of the patients had one single lesion. According the histological features of the lesions, JXG was classified into four subtypes in those patients： early JXG （ 24. 51%） , classical JXG （ 47. 06%） , transi-tional JXG （16.18%） and mixed JXG （12.25%）. Immunohistochemistry showed positive of CD68, negative of CD1a and S-100. Surgical excision are the major strategy for treatment.

关 键 词：皮肤幼年性黄色肉芽肿 病理特点 免疫组化 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]