吉林省山区儿童大骨节病患病现状及其影响因素调查  

Prevalence and influencing factors of Kashin-Beck disease among children in mountain areas of Jilin Province

作　　者：刘艳[1] 许舒野[2] 张雪英[2] 蒋媛媛[2] 吴冠宇[1] 王硕[1] 赵淑华[1] 

机构地区：[1]吉林大学公共卫生学院,长春130021 [2]吉林省地方病第二防治研究所

出　　处：《中华地方病学杂志》2015年第7期501-503,共3页Chinese Journal of Endemiology

基　　金：重大公共卫生服务地方病防治项目（2012）

摘　　要：目的了解吉林省山区儿童大骨节病的流行现状和影响因素。方法2012年，在吉林省山区，采用分层整群抽样法，抽取18个病区县（市）、282个病区村，依据《大骨节病诊断》（WS／T207．2010）标准，临床和X线检查病区村全部7-12岁儿童大骨节病病情，同时对调查区域家庭2009—2011年经济收入水平以及改种经济作物、外购换粮、退耕还林草比例进行调查。结果被调查的14162名儿童均无临床症状，X线检查阳性者28名，且主要表现为干骺端阳性，X线总检出率为1．98‰。2009—2011年平均年人均收入35000元地区，儿童大骨节病X线检出率明显小于年人均收入〈5000元地区（1．47‰vs．3．67‰，χ2=6．179，P〈0．05）；而退耕还林草占原耕地面积比例〉1％地区和≤1％地区儿童大骨节病X线检出率比较，差异无统计学意义（3．30‰vs．1．57‰，χ2=3．876，P〉0．05）；改种经济作物占原耕地面积〉10％地区和≤10％地区儿童大骨节病X线检出率比较，差异无统计学意义（3．07‰V8．1．65‰，χ2=2．565，P〉0．05）；外购换粮比例〉50％地区和≤50％地区儿童大骨节病X线检出率比较，差异无统计学意义（3．07％。V8．1．65‰，χ2=2．565，P〉0．05）。结论2012年吉林省山区7—12岁儿童基本达到了大骨节病消除标准，病情处于稳定状态。家庭经济收入水平可能是大骨节病发病的影响因素。Objective To understand the epidemic status quo and influencing factors of Kashin-Beck disease among children in mountain areas of Jilin Province. Methods Two hundred eighty-two severe endemic areas in 18 counties were selected and stratified by random cluster sampling method, and the status quo of Kashin- Beck disease prevalence was investigated among 7 - 12 year-old children according to the ＂Diagnostic Criteria of Kashin-Beck Disease＂ （WS/T 207-2010）. In the meantime, the annual household income and the proportion of economic crops replanted, grain out-sourced, and returning farmlands to forests and grass were surveyed in the disease affected areas. Results A total of 14 162 children were investigated who had no clinical symptoms. Among them, 28 cases were detected positive using X-ray with a detection rate of 1.98%o, while most of the cases were metaphysis positive. The annual household income （≥ 5 000 Yuan vs. 〈 5 000 Yuan） in the year 2009 - 2011 had a significant impact on the incidence of Kashin-Beck disease （1..47‰ vs. 3.67‰, χ2 = 6.179, P 〈 0,05）, while the areas of returning farmland to forests and grass which accounted 〉 1% had no significant influence on the incidence compared with that ≤1% （3.30%0 vs. 1.57‰, χ2 = 3.876, P 〉 0.05）; the areas of economic crops replanting which accounted 〉 10% had no significant influence on the incidence compared with that ≤ 10% （3.07%0 vs. 1.65‰, χ2 = 2.565, P 〉 0.05）; the proportion of grain out-sourcing which accounted 〉 50% had no significant influence on the incidence compared with that ≤50% （3.07%0 vs. 1.65%o, χ2 = 2.565, P 〉 0.05）. Conclusion Up to 2012, the disease among 7 - 12 year-old children of the mountain areas of Jilin Province have basically met the standard of Kashin-Beck disease elimination and the situation remains stable; furthermore, the household income has a significant impact on the incidence of Kashin-Beck disease.

关 键 词：大骨节病 流行病学研究 数据收集 

分 类 号：R726.8[医药卫生—儿科]