吉林省西部牧区牧民骨质疏松和骨量减少患病现状及影响因素研究  

Prevalence of osteoporosis and osteopenia and related influencing factors among herdsmen in the western pastoral areas of Jilin Province

作　　者：朱鹤[1] 甄清[2] 刘凡瑜[2] 关超玲 孙和平 李晔 王迪 姚燕[2] 杨芳[1] 

机构地区：[1]吉林大学第一医院胃肠内科内镜中心,长春130021 [2]吉林大学公共卫生学院流行病与卫生统计学教研室 [3]转化医学院临床药理中心 [4]吉林省地方病防治第一研究所 [5]吉林省松原市前郭尔罗斯蒙古族自治县疾病预防控制中心地方病防治科

出　　处：《中华地方病学杂志》2015年第7期504-507,共4页Chinese Journal of Endemiology

基　　金：国家自然科学基金青年基金（81102163）

摘　　要：目的了解吉林省西部牧区牧民骨质疏松和骨量减少患病情况，并探讨其可能影响因素。方法采用多阶段抽样方法，于2012年12月在吉林省西部牧区松原市前郭尔罗斯蒙古族自治县，抽取2个乡镇（查干花镇和乌兰塔拉乡），每个乡镇抽取50％的村子，以村中18岁以上养殖羊的牧民作为调查对象。采用定量超声骨密度测量仪对调查对象足跟骨进行骨密度测定；以面对面访谈方式，采用自行设计的调查表对调查对象进行问卷调查，内容包括一般人口学信息（年龄、性别、身高、体重、文化程度和婚姻等），肥胖状况[计算体重指数（BMI）]和骨质疏松相关因素等。采用χ2检验或秩和检验进行组间比较，Logistic回归多因素分析可能影响因素。结果共调查203名牧民，骨质疏松检出率为3．45％（7／203），骨量减少检出率为46．80％（95／203）。年龄350岁牧民患骨质疏松或骨量减少的风险是年龄〈40岁牧民的2．72倍[比值比（OR）=2．72，95％可信区间（C1）：1．34～5．53]；BMI18．5－〈24．0和≥24．0的牧民患骨质疏松或骨量减少的风险分别是BMI〈18．5牧民的0．21倍（OR=0．21，95％CI：0．06—0．79）和0．13倍（OR=0．13，95％CI：0．03—0．48）。性别、民族、每天饮酒量、父母骨质疏松疾病史、服用激素类药物史等因素与骨质疏松或骨量减少间相关性分析无统计学意义（P均〉0．05）。结论吉林省西部牧区牧民骨量减少检出率较高，年龄、BMI是影响骨质疏松或骨量减少患病的独立影响因素。Objective To investigate the prevalence and relevant risk factors of osteoporosis and osteopenia among herdsmen in the western pastoral arras of Jilin Province, so as to provide a scientific basis for prevention and control of the disease in pastoral areas. Methods A multi-stage sampling method was used to select areas to perform epidemiological investigation in December 2012. Two countries-Cha Ganhua and Wulantala ware randomly selected in Qianguo town. In each township, almost 50% of the villagers who were more than 18 years old were selected to detect osteoporosis and collect relevant information. Quantitative ultrasound bone density measuring instrument was used to measure the bone mineral density of subjects. Self-designed questionnaire was used to collect information. Information of general demographic information （age, gender, stature, weight, education level and marital status）, obesity status [body mass index （BMI）] and osteoporosis related influencing factors were included in the questionnaire. χ2 test and rank test were performed to compare differences between two groups. Multiple logistic regression analysis was used to analyze the independent influencing factors. Results Among 203 qualified subjects, detectable rates of osteoporosis and osteopenia were 3.45% （7/203） and 46.80% （95/203）, respectively. Age and BMI were two independent influencing factors of osteoporosis/osteopenia. Herders who were greater than 50 years old were 2.72 times riskier than those who were less than 40 years old to be suffered from osteoporosis or osteopenia （OR = 2.72, 95%CI： 1.34 - 5.53）; those with BM[ 〉-18.5 hut 〈 24.0 were 0.21 times riskier than those with BMI 〈 18.5 （OR = 0.21, 95%CI： 0.06 - 0.79）; those with BMI -〉24.0 were 0.13 times riskier than those with BMI 〈 18.5 （OR = 0.13, 95%CI： 0.03 - 0.48）. There were no statistical correlations between osteoporosis/osteopenia and sex, minority, drinking status, parents＂ history of osteoporosis, and glucocorticoid hormone usag

关 键 词：骨质疏松 骨量减少 危险因素 

分 类 号：R580[医药卫生—内分泌]