实时三维超声心动图评价正常新生儿左心室收缩功能的初步研究  

Preliminary study of the left ventricular systolic function by real-time three-dimensional echocardiography in normal newborns

作　　者：徐敏[1] 胡倩[1] 任卫东[1] 毛健[1] 毕文静[1] 胡金玲[1] 

机构地区：[1]中国医科大学附属盛京医院,辽宁沈阳110004

出　　处：《中国临床医学影像杂志》2015年第7期480-482,共3页Journal of China Clinic Medical Imaging

基　　金：辽宁省科技厅科学技术计划项目(2013225049)

摘　　要：目的:探讨实时三维超声心动图(RT-3DE)测量正常新生儿左心室容积及收缩功能的可行性及准确性。方法:回顾性分析我院接受RT-3DE检查的93例正常新生儿,应用3DQ Advance软件测量左室舒张末期容积(LVEDV)、收缩末期容积(LVESV)、每搏量(SV)及左心室射血分数(LVEF)。同时应用二维超声心动图(2DE)双平面Simpson法测量LVEDV、LVESV、SV及LVEF值,并对两者的检测指标结果进行相关性分析。探讨性别、胎龄、出生体质量和心率对各检测指标的影响。结果:RT-3DE所得LVEDV、SV、LVEF均值略大于2DE双平面Simpson法所得均值,且差异具有统计学意义(P<0.001);而LVESV均值RT-3DE稍小于2DE(P>0.05)。两种方法检测的LVEDV、LVESV、SV及LVEF值之间均具有高度相关性(r=0.94、0.87、0.94和0.75,P均<0.001)。性别、胎龄、心率对RT-3DE检测的LVEDV、LVESV、SV及LVEF值均无影响,而出生体质量与LVEDV、LVESV、SV存在正相关关系,对LVEF则无影响。结论 :RT-3DE作为一种无创的、崭新的三维成像技术,能够全面、快速、准确定量正常新生儿左心室容积及收缩功能,具有广泛的临床应用前景。Objective： To evaluate left ventricular（LV） volume and LV systolic function with real-time three-dimensional e- choeardiography （RT-3DE） in normal newborns. Methods： A retrospective review of 93 normal newborns with RT-3DE were performed, the LV end diastolic volume （LVEDV）, LV end systolic volume （LVESV）, stroke volume （SV） and LVEF were mea- sured by 3DQ Advance analysis. At the same time, the LVEDV, LVESV, SV and LVEF from biplane Simpson＇s method were measured as well. To evaluate whether they were affected by gender, gestational age, birth weight and heart rate. Results： There were significant differences between RT-3DE and biplane Simpson＇s method for LVEDV, SV and LVEF （P〈0.01）. There was excellent correlation between RT-3DE and biplane Simpson＇s method for LVEDV, LVESV, SV and LVEF （r=0.94, 0.87, 0.94, 0.75, P〈0.001）. Gender, gestational age and heart rate did not affect any of these parameters, while birth weight corre- lated positively with LVEDV, LVESV, SV. Conclusion： As a non-invasive 3D imaging technology, the RT-3DE can quantify LV volume and systolic function rapidly and accurately with clinical significance.

关 键 词：心室功能 左 超声心动描记术 婴儿 新生 

分 类 号：R331.31[医药卫生—人体生理学] R540.45[医药卫生—基础医学]