慢性阻塞性肺疾病急性加重期患者血沉、血清超敏C反应蛋白测定的研究  

Research of erythrocyte sedimentation rate and serum high sensitivity C-reactive protein detection in acute exacerbation of chronic obstructive pulmonary disease patients

作　　者：刘海波[1] 林颖[1] 

机构地区：[1]肇庆市第一人民医院呼吸内科,526000

出　　处：《中国现代药物应用》2015年第16期18-19,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨慢性阻塞性肺疾病急性加重期(AECOPD)患者血清超敏C反应蛋白(hs-CRP)测定的临床意义。方法 180例AECOPD患者,对治疗前后血清hs-CRP、血常规、血沉的变化进行比较。结果治疗后AECOPD患者血清hs-CRP浓度、白细胞总数、中性粒细胞总数、血沉均明显低于治疗前,比较差异均有统计学意义(P<0.05)。结论血清hs-CRP可作为判断AECOPD患者治疗疗效的一种炎症指标,有助于AECOPD的临床诊断和疗效观察。Objective To investigate clinical significance of serum high sensitivity C-reactive protein（hs-CRP） detection in acute exacerbation of chronic obstructive pulmonary disease（AECOPD） patients. Methods A total of 180 AECOPD patients were selected. Changes of their serum hs-CRP, blood routine examination, and erythrocyte sedimentation rate were compared before and after treatment. Results After treatment, serum hs-CRP, total white blood cells, total neutrophile granulocyte, and erythrocyte sedimentation rate in AECOPD patients were obviously lower than those before treatment. Their differences all had statistical significance（P〈0.05）. Conclusion Serum hs-CRP, as an inflammatory index for curative effect judgment, is helpful for clinical diagnosis and curative effect observation for AECOPD.

关 键 词：慢性阻塞性肺疾病急性加重期 血清超敏C反应蛋白 白细胞总数 血沉 

分 类 号：R563.9[医药卫生—呼吸系统]