植物油脚中植物甾醇作为甾体药物原料的发展前景  

Prospects of phytosterol from vegetable oil residue as raw materials for steroid drugs

作　　者：吴庆安[1,2] 吴红卫[1] 柏挺[2] 

机构地区：[1]浙江工业大学化学工程学院,杭州310014 [2]上海新华联制药有限公司,上海201400

出　　处：《现代化工》2015年第7期4-6,8,共4页Modern Chemical Industry

基　　金：上海市2014年度"科技创新行动计划"生物医药领域产学研医合作项目(14DZ1930100)

摘　　要：根据国内薯蓣资源现状,提出了植物甾醇作为甾体药物原料的理论依据及现实意义。通过对我国主要食用植物油所占比重及其甾醇平均含量的分析,推测出植物甾醇在植物油脚中的年蕴含量至少有21万t,这将大大满足甾体药物生产的需要。不久的将来我国甾体制药行业将会步入合成原料多元化的时代。Based on the status of dioscoreaceae plants in China, the theoretical and practical significance of phytosterol as the raw material of steroid drugs are proposed. By analyzing the percentage of main edible vegetable oils and their average sterols content,the reserves of the sterols in vegetable oil residue are evaluated as at least 210 million kilograms each year, which will meet the needs of the production of the steroidal drugs. Steroidal pharmaceutical industry in China is also prospected to enter the era with diverse synthetic material in the future.

关 键 词：植物油脚 植物甾醇 甾体药物 薯蓣皂素 

分 类 号：TQ467.95[化学工程—制药化工]