毛皮动物毛色调控基因的研究进展  

Research progress on the controlling genes for the coat colors of fur animals

作　　者：徐桂利[1] 刘铮铸[1] 巩元芳[1] 冯敏山[1] 段玲欣[1] 吴建华[1] 郭秀玲[2] 陆奇玉 

机构地区：[1]河北科技师范学院动物科技学院,河北秦皇岛066004 [2]河北昌黎县畜牧发展局,河北昌黎066600

出　　处：《黑龙江畜牧兽医》2015年第7期52-54,共3页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家自然科学基金项目(31272412);河北省自然科学基金项目(C2013407101);河北省高等学校创新团队领军人才培育计划项目(LJRC004);河北省人才工程培养经费项目

摘　　要：狐、貉、貂等毛皮动物毛纤维颜色丰富,含有多种天然毛色,主要由遗传基因决定。掌握调控毛皮动物毛色基因的作用机制,可以有效控制毛皮动物毛色的转变。动物毛色表型与其体内黑色素的种类、数量、合成及分布有关。在动物皮肤组织中,MC1R基因、Agouti基因、TYR基因、CBD103基因、SILV基因和KIT基因都参与毛色的形成与调控,文章对这些调控毛皮动物毛色的候选基因、作用机理及其与毛色表型的相关性研究进行了综述。The colors of hair fiber in fox,raccoon,mink,and other fur animals,are rich and contain a variety of natural colors,which are mainly determined by the genetic gene. Mastering the mechanism of action of regulating and controlling the coat color genes from fur animals,can effectively control the changes in the coat colors of fur animals. The phenotypes of coat colors of animals are related to the types,quantity,synthesis and distribution of melanin in the body of animals. All of the MC1 R,Agouti,TYR,CBD103,SILV and KIT genes participate in the formation and regulation of coat colors in the skin tissues of fur animals. This paper summarizes the correlation study of these candidate genes to regulate and control the coat colors of fur animals,the mechanism of action and the phenotypes of the coat colors.

关 键 词：毛皮动物 毛色 调控 候选基因 作用机理 相关性 

分 类 号：Q78[生物学—分子生物学] S879.4[农业科学—畜牧兽医]