更年期妇女合并代谢综合征的影响因素研究  

Influencing Factors for Menopause Complicated With Metabolic Syndrome

作　　者：孙加鑫 席思思[1] 陈醒[1] 程小侠 吕世一[1,4] 朱灵平[2] 白文佩[1] 阎小妍[5] 

机构地区：[1]北京大学第一医院妇产科,北京市100034 [2]北京大学医学部全科医学学系 [3]通州区中西医结合医院妇产科 [4]广东省深圳市第九人民医院妇产科 [5]北京大学临床研究所

出　　处：《中国全科医学》2015年第19期2286-2289,共4页Chinese General Practice

摘　　要：目的了解更年期妇女代谢综合征(MS)的合并率,并探讨其影响因素。方法选取2012年7月—2013年6月,参加北京大学第一医院更年期综合管理一日门诊的394例更年期妇女为研究对象。根据各项代谢指标情况,将其分为代谢正常组(n=94)和MS组(n=71)。比较并分析两组妇女的一般情况和更年期症状,探讨其合并MS的影响因素。结果 (1)394例更年期妇女的MS合并率为18.0%(71/394)。(2)两组妇女年龄、文化程度、初潮年龄、BMI及绝经情况比较,差异有统计学意义(P<0.05);Logistic回归分析显示,年龄、文化程度、初潮年龄、BMI及绝经情况对更年期妇女合并MS的影响有统计学意义(P<0.05)。(3)两组妇女的围绝经期症状(KMI)评分(≥15分)比较,差异无统计学意义(P>0.05);而眩晕,头痛,骨关节痛、肌肉痛症状比较,差异有统计学意义(P<0.05);Logistic回归分析显示,眩晕和骨关节痛、肌肉痛症状对更年期妇女合并MS的影响有统计学意义(P<0.05)。结论更年期妇女的MS合并率较高,年龄、文化程度、初潮年龄、BMI及绝经情况,眩晕和骨关节痛、肌肉痛症状为其影响因素。Objective To investigate the status of menopause complicated with metabolic syndrome（ MS） and its influencing factors. Methods A total of 394 menopausal women who received outpatient service of integrated menopausal management provided by Peking University First Hospital from July 2012 to June 2013 were enrolled and divided into normal metabolism group（ n = 94） and MS group（ n = 71）. The general data and menopausal symptoms were analyzed and compared between the two groups. And the influencing factors for menopause complicated with MS were also investigated. Results（ 1）Among the 394 subjects,the prevalence of menopause complicated with MS was 18. 0%（ 71 /394）.（ 2） The two groups were significantly different（ P 0. 05） in age, education level, age of menarche, BMI and menopausal status; the logistic regression analysis showed age,education level,BMI,age of menarche and menopausal status had significant influence（ P 0. 05） on menopause complicated with MS.（ 3） The two groups were not significantly different（ P 0. 05） in KMI（ ≥15）,while they were significantly different（ P 0. 05） in dizziness,joint pains and muscle pains,headaches; the logistic regression analysis showed dizziness,joint pains and muscle pains had significant influence（ P 0. 05） on menopause complicated with MS. Conclusion The prevalence of metabolic syndrome in menopausal women is high. Age,education level,age of menarche,BMI,menopausal status,dizziness,joint pains and muscle pains are influencing factors for menopause complicated with MS.

关 键 词：代谢综合征 更年期 影响因素分析 

分 类 号：R173[医药卫生—妇幼卫生保健]