药物不良反应发生与年龄及给药方式等关系的探讨  

作　　者：杜正虎[1] 赵晓冬[1] 

机构地区：[1]四川省射洪县人民医院,四川射洪629200

出　　处：《中文科技期刊数据库（引文版）医药卫生》2015年第2期72-72,共1页

摘　　要：探讨药物不良反应发生特点。方法:回顾分析220例药物不良反应患者,对年龄段、给药途径、药品种类、累及器官/系统及临床表现、严重程度分级等数据进行统计学分析。结果:老年患者(60岁以上)ADR发生率明显高于其他年龄组患者(33.18%),差异有统计学意义(P〈0.05)。静脉推注给药发生ADR比例最高(83.64%),差异有统计学意义(P〈0.05)。ADR药品以抗感染药物为主(69.54%),显著高于其他药品(P〈0.05)。以皮肤及其附件损伤为最多(37.73%)。严重程度一般为主(65%),显著高于其他严重程度患者(P〈0.05)。结论:通过回顾分析药物不良反应发生情况,及时发现尽早处理ADR,可有效降低药品不良反应的发生。Objective To investigate the occurrence of adverse drug reactions. MethodsRetrospecfive analysis of 220 cases of adverse drug reactions in patients, drug kinds,involving the organ system and clinical manifestations, severity of data were statistically analyzed. Results in elderly patients ( above 60 years old)ABR rate was significantly higher than that of other age groups( 33.18% )patients ,the difference was statistically significant( P 〈 0.05 ). significantly higher than that of other drugs( P 〈 0.05 ). significantly higher than the other severity of the patients( P 〈 0.05 ). Conclusion through the retrospective analysis of adverse drug reactions ,can effectively reduce the occurrence of adverse drug reaction.

关 键 词：给药途径 

分 类 号：R917[医药卫生—药物分析学]