正常形态前向运动精子总数对体外受精受精率的影响  

Before normal form to the total number of sperm movement and in vitro fertilization fertility rate analysis of the relationship

作　　者：高彩凤[1] 余相[1] 陈志云[1] 刘利敏[1] 李敦高[1] 

机构地区：[1]惠州市中心人民医院生殖医学中心,广东惠州516008

出　　处：《中国临床药理学杂志》2015年第14期1382-1383,1414,共3页The Chinese Journal of Clinical Pharmacology

基　　金：惠州市(医疗卫生)科技计划基金资助项目(2014Y014)

摘　　要：目的探讨正常形态前向运动精子总数对体外受精（IVF）受精率的影响。方法选取第1次进行常规体外受精-胚胎移植周期治疗的108对不孕夫妇分为A组、B组和C组。A组为正常形态前向运动精子总数0-0.4×106/m L,B组为正常形态前向运动精子总数0.4-1.8×106/m L,C组为正常形态前向运动精子总数〉1.8×106/m L。对取卵前半年内的平均正常形态前向运动精子总数和体外受精受精率的数据进行回顾性统计分析,分析正常形态前向运动精子总数和体外受精受精率之间的关系。结果 C组的体外受精受精率为91.02%显著高于A组60.38%和B组76.06%的体外受精受精率,差异有统计学意义（P〈0.01）。结论正常形态前向运动精子总数大于0.4×106时,可获得稳定的体外受精率。Objective To investigate the impact of total number of normal forward and progressive motility sperm（ TNNPS） on the rate of in vitro fertilization（ IVF）. Methods A total of 108 infertile patients who had operations for in vitro fertilization-embryo transfer treatment firstly was divided into group A,group B and group C. Group A was total number of normal form and progressive motility sperm（ TNNPS） 0-0. 4 ×106/ m L. Group B was TNNPS 0. 4-1. 8 × 106/ m L. Group C was TNNPS 1. 8 × 106/ m L. The mean TNNPS and IVF fertilization rate at6 months before treatment were obtained. The relation of TNNPS and IVF fertilization rate were analyzed. Results The IVF fertilization rate of group C was 91. 02% and it was significantly higher than 60. 38% in group A and 76. 06% in group B（ P〈0. 01）. Conclusion TNNPS was one of most important impaction in IVF fertilization. It could be an indicator for evaluation of sperm quality and it showed a tendency towards choose for clinical treatment programs.

关 键 词：前向运动精子 体外受精 受精率 

分 类 号：R321.2[医药卫生—人体解剖和组织胚胎学]