酮症倾向糖尿病病因及分型研究  

Pathogenesis and Classification of Ketosis-prone Diabetes

作　　者：赵宇洁[1] 邓志明[2] 

机构地区：[1]中南大学湘雅医院内分泌科,长沙410000 [2]常德市第一人民医院内分泌科,湖南常德415000

出　　处：《医学综述》2015年第13期2409-2411,共3页Medical Recapitulate

摘　　要：酮症倾向糖尿病(KPD)是一类以糖尿病酮症酸中毒或自发性酮症起病的糖尿病总称,既包括经典1A型糖尿病、成人隐匿性自身免疫糖尿病、特发性糖尿病,也包括以酮症酸中毒或糖尿病酮症起病的2型糖尿病。多种证据表明KPD是一类异质性疾病,KPD患者在遗传、发病机制、临床表现及β细胞功能储备上均存在差异。KPD合理分型,对研究其病因、发病机制,及血糖接近正常的缓解期治疗方案具有重要意义。Ketosis-prone diabetes （KPD） is a heterogeneous syndrome characterized by diabetes ketoac-idosis or unprovoked ketosis,which includes classic type 1A diabetes,latent autoimmune diabetes in adults, idiopathic diabetes and type 2 diabetes which with diabetes ketoacidosis or ketosis as onset .There are various of evidences indicating that KPD is a kind of heterogeneous disease,KPD patients have differences in genet-ics,pathogenesis,clinical manifestations,and β-cell function reserves.Reasonable classification of KPD is important to study the etiology,pathogenesis and treatment on near-normoglycemic remission.

关 键 词：酮症倾向糖尿病 病因 诊断 分型 

分 类 号：R587.1[医药卫生—内分泌]