利多卡因与阿替卡因对下颌磨牙不可复性牙髓炎麻醉疗效比较  

Comparison of Anesthetic Efficacy between Lidocaine and Articaine for Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis of Mandibular Molar

作　　者：张子川[1] 李晓燕[2] 

机构地区：[1]解放军白求恩国际和平医院口腔科,石家庄050082 [2]河北医科大学第三医院口腔正畸科,石家庄050051

出　　处：《解放军医药杂志》2015年第7期81-84,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的比较2%利多卡因和4%阿替卡因对下颌磨牙不可复性牙髓炎的下牙槽神经阻滞麻醉的效果。方法选取2014年7—12月108例确诊为不可复性牙髓炎的患者,随机分为A、B两组,每组54例,以双盲的方式分别给予1.7 ml 2%利多卡因、1.7 ml 4%阿替卡因行下牙槽神经阻滞麻醉。牙髓活力电测试仪读数为80,同时患者无主观感觉时,记录麻醉起效时间。采用视觉模拟评分量表(VAS)评价麻醉效果。结果与A组比较,B组麻醉起效时间缩短(P<0.05)。A、B组麻醉成功率分别为87.04%和92.59%(P>0.05)。A组VSA评分相应的毫米值长于B组(P<0.05)。结论对于下颌磨牙不可复性牙髓炎,4%阿替卡因的下牙槽神经阻滞麻醉效果优于2%利多卡因。Objective To compare the anesthetic efficacy of 2% Lidocaine and 4% Articaine for inferior alveolar nerve block（ IANB） in patients with irreversible pulpitis of mandibular molar. Methods A total of 108 patients with irreversible pulpitis of mandibular molar from July to December 2014 were randomly divided into group A（ n = 54） and group B（ n = 54）. Group A and B respectively received 1. 7 ml 2% Lidocaine and 1. 7 ml 4% Articaine by double-blind manner in IANB. Onset of anesthesia recorded when no subjective feeling responded and the reading of electronic pulp tester was 80. Visual analogue scales（ VAS） was used to evaluate the anesthetic effects of patients. Results Compared with that in group A,onset duration was significantly shorter in group B（ P 0. 05）. The successful rates of pulp anesthesia in group A and B were 87. 04% and 92. 59% respectively（ P 0. 05）. The corresponding millimeter value of VAS score in the group A was significantly longer than that in group B（ P 0. 05）. Conclusion The anesthetic efficacy of4% Articaine is superior to that by 2% Lidocaine for inferior alveolar nerve block in patients with irreversible pulpitis of mandibular molar.

关 键 词：阿替卡因 利多卡因 牙髓炎 麻醉和镇痛 

分 类 号：R971.2[医药卫生—药品] R781.31[医药卫生—药学]