全国225家实验室D-二聚体决定限的调查与分析  

National wide survey and analysis on decision limits of D-Dimer in 225 laboratories

作　　者：何法霖[1] 王薇[1] 钟堃[1] 张妍[1] 赵彦[1] 李国华[1] 王治国[1] 

机构地区：[1]卫生部北京医院卫生部临床检验中心,100730

出　　处：《中华检验医学杂志》2015年第7期490-492,共3页Chinese Journal of Laboratory Medicine

基　　金：北京市自然科学基金（7143182）

摘　　要：目的统计并描述2014年全国225家回报D-二聚体决定限。方法选择卫生部临床检验中心2014年全国D-二聚体室间质量评价回报结果中参评单位的决定限信息，剔除所有妇幼保健院、儿童医院和各类公司的结果，再剔除所有异常值和错误数据，使用Mierosoft Excel2007对225家实验室进行统计分析，包括平均值、中位数、最小值、最大值、P2.5和P97.5。统计决定限来源，同时对数据进行筛选，保留决定限来源于试剂厂家说明书的数据，再根据不同的试剂进行分组统计，试剂使用单位数〈5家的不统计。结果对决定限情况的调查显示：均值和中位数较为接近，P2.5和P97.5分布范围为：D-二聚体（DDU）0．3～1．33μg/ml，D-二聚体（FEU）0．23—1．50μg／mL，差异明显。结论此次调查D-二聚体决定限的均值和中位数较为接近，各项目P2.5和P97.5分布一致性很差。Objective To calculate and describe the decision limits of 2014 external quality assessment（EQA） programs in D-Dimer of 225 labs. Methods To eollectedtbe information of decision limits which come from the 2014 External Quality Assessment （EQA） programs in D-Dimer. All data from maternal and child care service centers, children＇s hospitals and corporations were excluded. Then all the abnormal values and errors were eliminated either. Data of 225 labs statistics were processed by Microsoft Excel 2007, which include the mean, median, maximum value, minimum value, P2.5 and P97.5. Weanalyzed the sources of decision limits and then get the data filtered. The reagent manufacturer＇s instructions data are reservedas a reference source and data are analyzed according to differentreagents. Results According to the surveys of decision limits sources, most of thereference sources use the reagent manufacturer＇s instructions. According to the surveys,the mean and median of each test project is close. The P2.5 and P97.5 distribution ranges are ： D-Dimer （ DDU ） 0.3 - 1.33 μg/ml, D-Dimer （ FEU ） 0.23 - 1.50 μg/ml, with significant differences. According to the surveys, most P2.5 and P97.5 reagent distributions are significantly different. Conclusion The decision limitsof the mean and median of each test item are approximate, and the P2.5and P97.5 distributions of each test item are poorly consistent.

关 键 词：实验室 医院 纤维蛋白纤维蛋白原降解物 参考值 

分 类 号：R446.1[医药卫生—诊断学]