早产儿出院时宫外发育迟缓的危险因素分析  

Risk factors for extrauterine growth retardation at discharge in premature infants

作　　者：蔡岳鞠[1] 宋燕燕[1] 黄志坚[1] 李坚[1] 肖旭文 齐俊冶 王兰秀[1] 

机构地区：[1]广州医科大学附属广州市妇女儿童医疗中心新生儿科,广东广州510623

出　　处：《中国当代儿科杂志》2015年第7期659-662,共4页Chinese Journal of Contemporary Pediatrics

摘　　要：目的：探讨早产儿出院时宫外发育迟缓（EUGR）发生率及相关危险因素。方法回顾性分析2006-2010年入住NICU的596例早产儿的临床资料，根据出院时体重分为EUGR组（n=217）与非EUGR组（n=379），应用logistic多因素回归分析EUGR发生的危险因素。结果596例早产儿按体重、身长、头围评价，出院时EUGR的发生率分别为36.4%（217例）、42.0%（250例）、22.8%（136例）。小胎龄、低出生体重、宫内发育迟缓（IUGR）、首次肠道喂养时间晚及呼吸系统合并症是早产儿发生EUGR的危险因素（OR分别为6.508、14.522、5.101、1.366、1.501）。结论加强母亲围产期保健，减少早产的发生，减少IUGR的发生，尽早进行肠道喂养，积极防治生后合并症对降低EUGR的发生率有较大意义。ObjectiveTo study the incidence and risk factors for extrauterine growth retardation （EUGR） at discharge in premature infants.MethodsA retrospective analysis was performed on 596 premature infants who were admitted to the neonatal intensive care unit between 2006 and 2010. These subjects were classiifed into EUGR （n=217） and non-EUGR groups （n=379） based on the body weight at discharge. The risk factors for the occurrence of EUGR were studied by multivariate logistic regression analysis.ResultsBased on the body weight, length, and head circumference, the incidence of EUGR at discharge was 36.4% （217 cases）, 42.0% （250 cases）, and 22.8% （136 cases）, respectively. Low gestational age, low birth weight, intrauterine growth retardation （IUGR）, delayed enteral feeding and complications of the respiratory system were identiifed as risk factors for EUGR （OR=6.508, 14.522, 5.101, 1.366, and 1.501, respectively）.ConclusionsThe incidence of EUGR might be greatly decreased by strengthening the perinatal care, reducing the incidence of premature delivery and IUGR, undertaking early enteral feeding, and actively preventing postnatal complications.

关 键 词：宫外生长发育迟缓 危险因素 早产儿 

分 类 号：R722.6[医药卫生—儿科]