肾部分切除术后影响术肾功能的相关因素分析  

Related risk factors of renal function after partial nephrectomy

作　　者：郭德迎 张新明[1] 李坚伟[1] 徐华[1] 陈巧莲[1] 

机构地区：[1]深圳市蛇口人民医院泌尿外科,广东深圳518067

出　　处：《局解手术学杂志》2015年第4期422-424,共3页Journal of Regional Anatomy and Operative Surgery

摘　　要：目的探讨影响肾部分切除术患者术肾的相关危险因素,为临床的防治提供参考。方法收集我院自2010年1月至2014年6月收治的31例小肾癌(最大直径小于等于4.0 cm)患者的临床资料,对治疗前后术肾肾小球滤过率(GFR)的变化与临床病理因素的关系进行分析,单因素分析采用t检验,多因素分析采用多因素非条件的Logistic回归分析。结果单因素分析结果显示,肾部分切除术患者术肾肾功能与年龄、合并糖尿病、阻断时间、肿瘤的大小、肾体积减少比例有相关性,差异有统计学意义(P<0.05);多因素非条件的Logistic回归分析显示肾部分切除术患者术肾肾功能与年龄、阻断时间、肾体积减少比例是影响术肾功能的相关(P<0.05)。结论年龄、阻断时间、肾体积减少比例是影响肾部分切除术患者术肾肾功能的危险因素。Objective To explore the related risk factors of renal function after partial nephrectomy,and provide the reference for clinic. Methods The data of 31 patients with small renal cancer in our hospital from January 2010 to June 2014 were analyzed. Before and after the treatment,the relationship of renal glomerular filtration rate（ GFR） with the change and clinical pathological factors were analyzed,the single factor analysis used t test,multiple factors analysis adopted multi-factor unconditioned logistic regression analysis. Results Single factor analysis results showed that renal function after partial nephrectomy was closely related to the age,diabetes mellitus,blocking time,the size of the tumor,renal volume reduction ratio,the difference was statistically significant（ P 〈0. 05）. Many factors of logistic regression showed that it was closely related to the age,blocking time,renal volume reduction ratio（ P 〈0. 05）. Conclusion The age,blocking time,renal volume reduction ratio are risk factors for renal function after partial nephrectomy.

关 键 词：小肾癌 肾部分切除术 肾功能 危险因素 

分 类 号：R699.2[医药卫生—泌尿科学]