胞必佳胸腔内注射治疗顽固性气胸的临床研究  被引量:3

Clinical study of intrapleural injection of N-CWS in the treatment of intractable pneumothorax

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作  者:林权[1] 陈孺子 林锐浩[1] 

机构地区:[1]广东省潮州市潮安区庵埠华侨医院内一科,潮州515638

出  处:《临床医学》2015年第6期9-11,共3页Clinical Medicine

摘  要:目的探讨胞必佳胸腔内注射对顽固性气胸的治疗作用。方法将96例顽固性气胸患者随机分为观察组(胞必佳组)和对照组(重组人白细胞介素-2组),在胸腔闭式引流的基础上,分别往胸腔内注入胞必佳400μg或重组人白细胞介素-2 150万IU。结果观察组用药后平均终止漏气时间为(1.89±0.95)d,有效率为91.7%,1次注药成功率为52.1%;对照组用药后平均终止漏气时间为(3.78±0.89)d,有效率为70.8%,1次注药成功率为20.8%,两组比较差异有统计学意义(P<0.05)。两组不良反应发生情况比较差异未见统计学意义(P>0.05),且均对外周血象无明显影响。结论胞必佳胸腔内注射治疗顽固性气胸效果佳,不良反应少。Objective To investigate the therapeutical effect of N-CWS intrapleural injection on intractable pneumothorax.Methods Ninety-six patients with refractory pneumothorax were randomly divided into observation group( N-CWS group) and control group( rh IL-2 group). Randomly injected 400 μg of N-CWS or 150 IU of rh IL-2 into the chest cavity on the basis of the chest closed drainage. Results The post-medication average end leaking time of the observation group was( 1. 89 ± 0. 95) d,the effective rate was 91. 7%,the first time injection success rate was 52. 1%; The post-medication average end leaking time of the control group was( 3. 78 ± 0. 89) d,the effective rate was 70. 8%,the first time injection success rate was 20. 8%. The differences between the two groups were significant( P〈0. 05). In the adverse reaction,there was no statistically significant difference between the two groups( P〉0. 05),and all cases had no affecting on the peripheral hemogram. Conclusion Intrapleural injection of N-CWS in the treatment of intractable pneumothorax has good effect and less adverse effect.

关 键 词:胞必佳 重组人白细胞介素-2 顽固性气胸 

分 类 号:R561.4[医药卫生—呼吸系统]

 

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