广州市越秀区及海珠区非结核分枝杆菌流行状况  

Epidemic situation of nontuberculous Mycobacteria at Yuexiu and Haizhu regions in Guangzhou

作　　者：童莉[1] 谭守勇[2] 刘志辉[2] 黄业伦[2] 黎燕琼[2] 

机构地区：[1]广州医科大学,510000 [2]广州市胸科医院结核科,呼吸疾病国家重点实验室,510095

出　　处：《实用医学杂志》2015年第13期2211-2213,共3页The Journal of Practical Medicine

基　　金：广东省科技计划项目(编号:2011B061300085);广州市医药卫生科技重点项目(编号:201102A212009)

摘　　要：目的:了解广州市越秀区及海珠区非结核分枝杆菌流行状况。方法:回顾性对广州市越秀区、海珠区两个结核病防治所2010-2012年就诊的痰抗酸杆菌涂片阳性可疑肺结核患者,进行痰结核分枝杆菌培养及菌种鉴定,分析肺结核诊断的准确性。结果:2010-2012年共2 014例痰涂片及培养抗酸杆菌阳性,1 630例(80.9%)为结核分枝杆菌复合群(MTC),384例(19.1%)为非结核分枝杆菌(NTM)。2010-2012各年度痰培养抗酸杆菌阳性菌株中,NTM分离率分别为17.6%、17.1%、21.2%。384株NTM中共有79株进行了NTM菌种或复合群鉴定,快速生长型分枝杆菌占50.6%,慢速生长型分枝杆菌占49.4%。结论:广州市越秀区、海珠区可疑肺结核患者痰标本中NTM分离率为19.1%。临床上对涂阳肺结核患者疗效欠佳时,应及时排除非结核分枝杆菌肺病。Objective To explore the epidemic situation of nontuberculous Mycobacteria in both Yuexiu and Zhuhai districts. Methods Mycobacterium tuberculosis culture and strain identification were conducted in suspected smear-positive tuberculosis patients who had visited our clinics at Yuexiu and Haizhu districts in Guangzhou during the period of 2010 to 2012. Results 2 014 sputum samples were identified as NTM and MTC, 1 630 samples were MTC （80.9%）, and 384 samples were NTM （19.1%）. The isolated rate for NTM from 2010 to 2012 was 17.6%, 17.1% and 21.2%, respectively. 79 strains of 384 NTM were identified; the rapid-growing myeobacterium was 50.6%, and the slow-growing mycobacterium was 49.4%. Conclusions The sputum-isolated rate of NTM for the suspected tuberculosis patients was 19.1% in Yuexiu and Haizhu districts in Guangzhou. For the smear-positive pulmonary tuberculosis patients who respond to treatment poorly, we should pay attention to NTM lung disease.

关 键 词：分枝杆菌 流行病学 非结核 

分 类 号：R446.5[医药卫生—诊断学]