静脉滴注抗生素联合外用双黄液治疗糖尿病足溃疡的临床分析  

Clinical Analysis of Using Antibiotics Intravenous Drip Combined with Shuanghuang Liquid External Use to Treat Diabetic Foot Ulcer

作　　者：徐绍娟[1] 胡爱民[2] 

机构地区：[1]首都师范大学社区卫生服务中心全科,北京100048 [2]空军总医院急诊科,北京100048

出　　处：《四川医学》2015年第7期989-992,共4页Sichuan Medical Journal

摘　　要：目的探讨在综合治疗基础上蚕食清创方法清除坏死组织后,静脉滴注抗生素联合外用双黄液治疗糖尿病足溃疡的临床效果。方法回顾性分析我院收治的120例糖尿病足溃疡患者的临床资料,均采用综合治疗措施,且均根据药敏试验结果静脉滴注抗生素,并采用蚕食清创方法清除坏死组织。对照组(n=60)清创后采用局部外用利凡诺纱条覆盖创面进行治疗;观察组(n=60)采用局部外用双黄液纱条覆盖创面进行治疗,静脉滴注治疗均以14d为1个疗程,相邻两个疗程间间隔5d。治疗2个疗程后观察两组的临床疗效。结果治疗2个疗程后,观察组溃疡面愈合总有效率为83.3%高于对照组的61.7%,差异有统计学意义(P<0.05);观察组溃疡面积、创面渗出、创面浸润带及肉芽生长疗效指数均高于对照组,差异有统计学意义(P<0.05);治疗后两组溃疡面经皮氧分压及p H差异均有统计学意义(P<0.05)。结论在综合治疗基础上,蚕食清创方法清除坏死组织后静脉滴注抗生素联合外用双黄液治疗糖尿病足溃疡临床疗效显著,有利于促进溃疡面的愈合,值得临床推广。Objective To analyze the curative effects of antibiotics intravenous drip combined with Shuanghuang liquid external use for the treatment of diabetic foot ulcer（ DFU）. Methods The clinical data of 120 patients in our hospital with diabetic foot ulcers were retrospectively analyzed,which all adopted comprehensive treatment measures,intravenous drip of antibiotics,and Eroded debridement to treat ulcers. After that,the control group（ 60 cases） used article rivanol gauze to cover wound treatment; And the observation group（ 60 cases） were given Shuanghuang liquid yarn to cover the wound; 14 days were as a period of intravenous therapy treatment,and there were five days interval between two period of treatment; After 2 courses of treatment,the clinical effects of two groups were compared and observed. Result After two courses of treatment,the total effective rate of healing ulcer surface in observation group was 83. 3%,significantly higher than that in the control group 61. 7%（ P〈0. 05）; The ulcer area,exudation,the infiltration of the wound and granulation growth curative effect index were significantly higher than the control group（ P〈0. 05）; After treatment ulcer surface percutaneous oxygen partial pressure and p H differences of the two groups were all statistically significant（ P〈0. 05）. Conclusion On the basis of comprehensive treatment,using antibiotics intravenous drip combined with Shuanghuang liquid external use to treat diabetic foot ulcer（ DFU） has distinct curative effects,which was beneficial to promote the ulcer healing,worthy of clinical promotion.

关 键 词：双黄液 糖尿病足溃疡 抗生素 

分 类 号：R587.2[医药卫生—内分泌]