缬沙坦与胺碘酮联合治疗对阵发性房颤患者左房大小和不应期影响  

The Influence of Left Atrial Diameter and the Left Atrial Refractory Period of Valsartan Combined with Amiodarone in Patients with Paroxysmal Atrial Fibrillation

作　　者：黄琦磊[1] 程显禄[1] 陈子国[1] 蒋凌[1] 王光友[1] 

机构地区：[1]福建医科大学附属南平第一医院,福建南平353000

出　　处：《中外医学研究》2015年第21期21-22,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:观察缬沙坦与胺碘酮联合治疗对阵发性房颤窦律维持的疗效。方法:将125例阵发性房颤患者随机分成试验组(n=63),对照组(n=62),两组患者均服胺碘酮,试验组加缬沙坦80 mg/d,疗程为18个月;比较两组房颤患者治疗18个月后左房内径值和不应期。结果:治疗18个月后对照组左房内径大于试验组(P<0.05),试验组左房不应期大于对照组(P<0.05)。结论:缬沙坦与胺碘酮联合治疗可减少左房的增大,延长左房不应期。Objective ： To observe the effect of Valsartan combined with Amiodarone therapy to maintain sinus rhythm of paroxysmal atrial fibrillation. Method： 125 cases with paroxysmal atrial fibrillation were randomly divided into the experimental group（n=63） and the control group（n=62）, they were treated with amiodarone, but the experimental group was increased Valsartao 80 mg every day; the treatment duration was 18 months, left atrial diameter and left atrial refractory period before and after the treatment of 18 months were compared in two groups.Result： After 18 months of treatment, the left atrial diameter in the control group was bigger than that in the experimental group, there was statistical significance（P〈0.05）, left atrial refractory period in the experimental group was bigger than that in the control group, there was statistical significance（P〈0.05）.Conclusion： The treatment with Valsartan combined with Amiodarone can reduce the increase of left atrial diameter and extend the left atrial refractory period.

关 键 词：房颤 缬沙坦 胺碘酮 

分 类 号：R541.75[医药卫生—心血管疾病]