氧驱雾化吸入布地奈德混悬液治疗小儿哮喘急性发作的疗效及其对肺功能的影响  

Effects of budesonide suspension by oxygen atomization inhalation in treatment of child with acute paroxysm of asthma

作　　者：翟红[1] 肖雪清[1] 

机构地区：[1]四川省双流县妇幼保健院小儿内科,四川双流610200

出　　处：《实用临床医药杂志》2015年第E01期64-65,共2页Journal of Clinical Medicine in Practice

摘　　要：目的探讨氧驱雾化吸入布地奈德混悬液治疗小儿哮喘急性发作的疗效及其对肺功能的影响。方法选取哮喘急性发作患儿116例，随机分为观察组和对照组，各58例，对照组予以吸氧、抗感染、止咳、平喘、祛痰、纠正水电解质平衡等常规治疗，观察组在此基础上予以布地奈德混悬液氧驱雾化吸入，观察2组临床疗效及肺功能改变情况。结果观察组总有效率为94．8％高于对照组的82．8％，差异有统计学意义（P〈0．05）。2组患者治疗后一秒用力呼气容积（FEV1）用力肺活量（FVC）、最大呼气流量（PEF）均高于治疗前，差异有统计学意义（P〈0．05，P〈0．01）；治疗后观察组上述指标改善优于对照组，差异有统计学意义（P〈0．01）。结论氧驱雾化吸入布地奈德混悬液治疗d,JD哮喘急性发作疗效显著，可有效改善肺功能。Objective To evaluate the application of budesonide suspension by oxygen atomi- zation inhalation in treatment of child with acute paroxysm of asthma and related effects on pulmonary function. Methods A total of 116 patients were randomly divided into study group （ n = 58） and con- trolled group（n = 58）. The controlled group was treated with conventional treatment, while the study group was treated with budesonide suspension by oxygen atomization inhalation. The clinical effect and changes in pulmonary function of two groups were compared. Results The total effective rate of study group（94.8% ） was significantly higher than that of controlled group （ 82.8% ） （ P 〈 0.05 ）. The forced expiratory volume in 1 second （FEV1）, forced vital capacity（FVC） and peak expiratory flow （PEF） were improved in both groups after treatment （P 〈0.05, P 〈 0.01 ）and were better improved in the study group （ P 〈 0.01 ）. Conclusion Treating acute paroxysm of asthma in children with budesonide suspension by oxygen atomization inhalation is effective.

关 键 词：布地奈德混悬液 雾化吸入 小儿 哮喘 肺功能 

分 类 号：R256.12[医药卫生—中医内科学]