BiPAP治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭的疗效分析  

Clinical Effect Observation of BiPAP Noninvasive Ventilation in the Treatment of Acute Excerbation of Chronic Obstructive Pulmonary Disease Respiratory Failure

作　　者：白小燕[1] 孟又胜[1] 廖俊喆 

机构地区：[1]四川省成都市第五人民医院呼吸科,四川成都611130

出　　处：《医学与社会》2015年第B05期97-97,共1页Medicine and Society

摘　　要：目的：探讨无创双水平气道正压（BiPAP）通气治疗慢性阻塞性肺疾病急性加重（AECOPD）合并呼吸衰竭临床疗效。方法：AECOPD合并呼吸衰竭90例，随机分为治疗组（BiPAP治疗组）及对照组（常规治疗组），每组45例，观察治疗前、治疗48h及治疗722小时患者的RR、HR、PC02、P02、PH及住院时间。结果：治疗48h后治疗组患者pH、PaO2、PaCO2、HR及RR的改善明显好于对照组（P〈0．05）；治疗组72h血气指标明显改善（P〈0．05），各项观察指标均显著好转（P〈0．05）；治疗组及对照组的住院时间分别为7．8±2．3，93±5．3，差异有统计学意义（P〈0．05）。结论：BiPAP是治疗AECOPD呼吸衰竭患者的有效手段，具有良好的应用前景。Objective：To explore the curative effect of Bilevel Positive Airway Pressure（BiPAP） noninvasive ventilation in treating acute exacerbation of chronic obstructive pul- monary disease（AECOPD） with respiratory failure. Methods：90 patient with AECOPD with respiratory failure were randomly divided into experimental group（45 ） and control group （45）. The control group was treated with the standard therapy and the experimental group Was treated with immediate BiPAP noninvasive ventilation mode based on the standard thera- py. Comparison was then made for arterial blood gas analysis, respiratory rate, heart rate between the groups. Results ： The blood PH, PaO2, PaCO2, respiratory rate, heart rate of the exper- imental group were obviously better than those of the control group after the treatment for 24 hours and 72 hours. The difference between the control and the experimental group Was statistically significant. Conclusions ： The clinical curative effect of BiPAP noninvasive ventilation in treatment of AECOPD with respiratory failure is significant and it is worth promoting.

关 键 词：BIPAP 慢性阻塞性肺疾病急性加重期 呼吸衰竭 

分 类 号：R273[医药卫生—中西医结合]