甲状腺癌根治术后甲旁减致继发性癫痫1例诊治体会  

Treatment of hypoparathyroidism complicated with secondary epilepsy after radical surgery of thyroid cancer

作　　者：王庆 彭丽萍 唐培志 

机构地区：[1]湘西自治州人民医院乳甲外科,湖南吉首416000

出　　处：《现代医学》2015年第6期758-760,共3页Modern Medical Journal

摘　　要：目的:提高对甲状旁腺功能减退症(甲旁减)低钙血症致继发性癫痫的诊疗认识。方法:分析1例甲旁减致继发性癫痫患者的临床资料,并结合文献进行讨论。结果:甲旁减患者术后长期低钙血症致全身多器官功能受损,其中脑细胞功能受损后易表现为脑基底节区钙化而引起继发性癫痫发作,这种罕见的继发性癫痫容易造成临床误诊,积极补钙治疗可以预防癫痫复发,无须常规抗癫痫治疗。结论:甲旁减致继发性癫痫罕见,临床表现为较为规律的癫痫发作,维持血钙正常是预防继发性癫痫的主要治疗手段。Objective： To improve the understanding of diagnosis and treatment of hypocalcemia induced from hypoparathyroidism leading to secondary epilepsy. Methods： The clinical data of a case of secondary epilepsy caused by hypoparathyroidism were analyzed and relative literatures were discussed. Results： Hypoparathyroidism patients after long- term hypocalcemia induced multiple organ dysfunction, which was easy after brain cell dysfunction manifested as cerebral basal ganglia calcification, causing secondary epilepsy, this rarely seen secondary epilepsy easily led to misdiagnosis,which could be cured with calcium supply. Conventional antiepileptic therapy was not needed. Conclusion： Hypoparathyroidism caused secondary epilepsy is rare; it clinically manifests regular seizures. Maintaining normal blood calcium is the main treatment for the prevention of secondary epilepsy.

关 键 词：甲状旁腺功能减退症 低钙血症 继发性癫痫 

分 类 号：R653[医药卫生—外科学]