恙虫病诊断方法研究进展  

Progress on diagnostic methods of tsutsugamushi disease

作　　者：陈琳[1] 赵锋[1] 孟菁[1] 王俊贤[1] 樊学军[1] 杨雨[1] 刘杨[1] 

机构地区：[1]四川国际旅行卫生保健中心,四川成都610041

出　　处：《中国国境卫生检疫杂志》2015年第1期67-71,共5页Chinese Journal of Frontier Health and Quarantine

基　　金：质检公益项目(201210046);国家质检总局科技计划项目(2013IK241;2012IK240);四川出入境检验检疫局科研项目(SK201404)

摘　　要：恙虫病又称丛林斑疹伤寒,是由恙虫病东方体引起的一种自然疫源性疾病。鼠类为主要传染源,恙螨为传播媒介。恙虫病的临床表现为叮咬部位焦痂或溃疡、发热、淋巴结肿大和皮疹,这些非特异症状极易导致误诊。近年来,分子生物学技术大量应用于恙虫病东方体的检测,有效提高了检测效率和检测结果的准确性。本文对恙虫病的病原学、流行病学以及实验室诊断技术进行了综述。Tsutsugamushi disease, known as scrub typhus, is a natural focus disease caused by Orientia tsutsugamushi.The disease is mainly spread by rats and chigger mites. The clinical manifestations of tsutsugamushi disease are bite eschar or ulcer, fever, swollen lymph nodes and rashes. These nonspecific symptoms can easily lead to misdiagnosis.Recently, the application of molecular biology technologies in tsutsugamushi disease detection, improve the detection efficiency and the accuracy of the test results effectively. In this article, the etiology of tsutsugamushi disease,epidemiology and diagnostic methods are reviewed.

关 键 词：恙虫病 恙虫病东方体 分子生物学诊断 

分 类 号：R183.5[医药卫生—流行病学]