右美托咪定对开胸手术连续胸椎旁神经阻滞术后镇痛效果的影响  

Effects of dexmedetomidine on postoperative analgesia with continuous thoracic paravertebral nerve block after thoracic operation

作　　者：田文华[1] 高嵩[1] 杨帆[1] 魏常 汤世玉 罗锋[1] 崔颖[1] 王磊[1] 

机构地区：[1]武汉市汉口医院麻醉科,430012

出　　处：《实用疼痛学杂志》2015年第1期46-48,共3页Pain Clinic Journal

摘　　要：目的观察右美托咪定对开胸手术后连续胸椎旁神经阻滞术后镇痛效果的影响。方法选择开胸手术60例，随机分成A组和B组，每组30例。A组为右美托咪定联合连续胸椎旁神经阻滞组，B组为单纯罗哌卡因胸椎旁神经阻滞。观察两组术后镇痛效果。结果术后各时点A组镇痛效果优于B组，且不良反应少，差异均有统计学意义（P〈0．05）。结论右美托咪定可增强开胸手术连续椎旁神经阻滞的术后镇痛效果，减少不良反应。Objective To observe the effects of dexmedetomidine on continuous thoracic paravertebral nerve block for analgesia after thoracic operation. Methods Sixty patients undergoing thoracic operation were randomly divided into group A and group B, 30 patients in each group. Patients were received dexmedetomidine combined with continuous thoracic paravertebral nerve block with ropivacaine in the group A, while patients only received thoracic paravertebral nerve block with ropivacaine in the group B. The analgesic effects of the two groups were observed. Results The analgesia effects were significantly better and side effects were lower in group A than those in group B （P 〈 0.05）. Conclusion Dexmedetomidine can enhance postoperative analgesic effects of paravertebral nerve block with ropivacaine after thoracic surgery, with fewer side effects.

关 键 词：右美托咪定 胸椎 神经传导阻滞 镇痛 胸外科手术 

分 类 号：R655[医药卫生—外科学]