乌鲁木齐市居民出血性脑卒中相关危险因素分析  

Relevant risk factors analysis on patients with hemorrhagic stroke between Uygur people and Han people in Urumqi

作　　者：郭敏[1] 成晓江[1] 麦麦提力.米吉提 买吾拉江.阿木提 阿力木江.阿不都卡地尔 买买提力.艾沙 

机构地区：[1]新疆医科大学第一附属医院神经外科,乌鲁木齐830054

出　　处：《新疆医科大学学报》2015年第8期1004-1007,共4页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区自然科学基金(2012211A071)

摘　　要：目的探讨新疆乌鲁木齐市居民出血性脑卒中发病的相关危险因素,为出血性脑卒中的个体化预防提供科学依据。方法采用前瞻性脑卒中登记方法,连续收集2012年1月-2014年6月新疆乌鲁木齐市8家医院维吾尔族、汉族经头颅CT或MRI确诊的出血性脑卒中患者800例(病例组),以同期8家医院维吾尔族、汉族健康体检者800例作为对照组,设计统一的调查表,进行脑卒中登记,分析出血性脑卒中的相关危险因素。结果病例组与对照组均显示年龄(P=0.001)、民族(P=0.010)、吸烟史(P=0.003)、饮酒史(P=0.026)、高血压病史(P=0.001)、糖尿病病史(P=0.012)、高脂血症病史(P=0.014)等因素是发生出血性脑卒中的危险因素;其中年龄(P=0.001)、族别(P=0.025)、吸烟史(P=0.000)、高血压病史(P=0.000)、糖尿病病史(P=0.027)、高脂血症病史(P=0.002)是发生出血性脑卒中独立危险因素;高血压病史(OR=4.471)对出血性脑卒中的影响最大。维吾尔族患者吸烟、饮酒比例明显低于汉族(P<0.001),而高脂血症的患病率高于汉族(P=0.023)。结论高血压、高脂血症、年龄、饮酒、吸烟、糖尿病是出血性脑卒中常见危险因素,维族、汉族的差异可能与基因、生活饮食习惯等密切相关,并且通过控制血压和血脂、合理膳食、改变不良的生活饮食习惯、加强锻炼等措施有利于预防出血性脑卒中的发生。Objective To compare and analyze the difference of risk factors in patients with hemorrhagic stroke in Xinjiang and provide a scientific basis for hemorrhagic stroke prevention. Methods A prospective stroke registration method was adopted to collect 800 cases of hemorrhagic stroke patients and 800 cases of normal people diagnosed by head CT or MRI from 8 hospitals in Urumqi of Xinjiang from 2012. 1- 2014. 6. Questionnaires were designed and the survey was conducted to register the stroke and analyze the risk factors of patients with hemorrhagic stroke. Results It was found out that risk factors of hemorrhagic stroke included age（ P〈0. 001）,ethnicity（ P= 0. 01）,smoking（ P = 0. 003）,drinking（ P = 0. 026）,history of high blood pressure（ P〈0. 001）,history of diabetes（ P = 0. 012）,history of hyperlipidemia（ P = 0. 014）,among which age（ P〈0. 001）,ethnicity（ P =0. 025）,smoking（ P〈0. 001）,history of high blood pressure（ P〈0. 001）,history of diabetes（ P = 0. 027）,history of hyperlipidemia（ P = 0. 002） were independent risk factors for hemorrhagic cerebral apoplexy. One of the biggest impact on hemorrhagic stroke was high blood pressure（ OR = 4. 471）. Compared with Han people with hemorrhagic stroke,Uygur patients had lower intake of smoking and alcohol（ P〈0. 001）,but higher incidence of hyperlipidemia（ P = 0. 023）. Conclusion Hypertension,hyperlipidemia,age,drinking,smoking,diabetes mellitus were common risk factors for hemorrhagic stroke. The differences between Uygur and Han people in the incidence of hemorrhagic stroke were considered to be closely related with gene,life habits and diet habits. It＇ advisable to control blood pressure and blood fat,dietary,change bad habits of life and strengthen exercise for the prevention of hemorrhagic stroke.

关 键 词：出血性脑卒中 危险因素 病例对照研究 

分 类 号：R543[医药卫生—心血管疾病]