2009年至2013年深圳市先天性心脏病监测结果分析  

Analysis of monitoring data on congenital heart disease in Shenzhen city from 2009 to 2013

作　　者：赖彩芹 王晨虹[1] 李胜利[2] 赵光临[3] 谷寅[4] 

机构地区：[1]南方医科大学附属深圳妇幼保健院产科,深圳518028 [2]南方医科大学附属深圳妇幼保健院超声科,深圳518028 [3]南方医科大学附属深圳妇幼保健院信息科,深圳518028 [4]南方医科大学附属深圳妇幼保健院麻醉科,深圳518028

出　　处：《中国医师杂志》2015年第7期1024-1027,1031,共5页Journal of Chinese Physician

基　　金：基金项目：深圳市科技计划资助项目（JCYJ20130402094134981）

摘　　要：目的 了解深圳市先天性心脏病（先心病）的基本流行病学特征.方法 描述先心病胎婴儿及其母亲的基本流行病学特征,并根据胎婴儿的畸形类型分为仅有心血管系统畸形的单纯型先心病组（简称单纯组）及合并有心血管系统畸形外其他系统畸形的复杂型先心病组（简称复杂组）,对其进行相关指标的统计描述分析.结果 五年深圳市先心病平均发生率7.25‰,呈上升趋势,其中94.36％依靠超声波检查发现,产前诊断率33.20％,孕妇年龄多在20 ～30岁,以单胎、男性、夏秋季出生者较多;最常见的心血管畸形是动脉导管未闭、室间隔缺损、房间隔缺损;并发心外系统畸形者占14.11％,以骨骼四肢系统、颜面五官、神经系统畸形多见.单纯组与复杂组年龄分层、文化程度、转归及诊断时间比较差异均有统计学意义（P＜0.01）.结论 先心病胎婴儿以超声波检查发现者为多,以单纯心血管系统畸形为主,且以≥2种多发心血管畸形多见;并发心外系统畸形的复杂型先心病的死胎率、产前诊断率、在30 ～40岁年龄段孕妇的胎婴儿先心病发病率均明显高于单纯型先心病.Objective To analyze monitoring data on congenital heart disease （CHD） in Shenzhen city from 2009 to 2013.Methods This study described epidemiological characteristics of perinatal CHD.Patients with CHD were divided into isolated CHD group and complex CHD group （the patients were found with malformations of other systems）.The prognosis,social and demographic characteristics,and complications of pregnancy were analyzed.Results The average incidence rate of CHD was 7.25‰,of which 94.36% were diagnosed by ultrasound,of which 33.20% were diagnosed before delivery.The top three cardiovascular abnormalities were patent ductus arteriosus,patent foramen ovale,and ventricular septal defect.There were about 14.11% of CHD with other system malformations,mainly including musculoskeletal system,facial features,and nervous system.Compared isolated cardiac malformations and complex cardiacmalformations,significant differences were found in the age stratification,culture degree,prognosis,diagnosis time,incidence rate of complication of pregnancy,and childbirth complications rate （P 〈0.01）.Conclusions Most CHDs were diagnosed by ultrasound.Simple cardiovascular malformation was common,especially CHD with two or more types of cardiovascular malformations.The incidence rate of CHD in 30 to 40-year-old women,stillbirth rate,incidence of prenatal diagnostic rate were significantly higher than the simple CHD group.

关 键 词：心脏缺损 先天性/流行病学 

分 类 号：R714.5[医药卫生—妇产科学]