氨氯地平阿托伐他汀钙片治疗高血压合并冠心病  

A Study on the Effect of Amlodipine Atorvastatin Calcium Tablet on Patients with Hypertension with Coronary Heart Disease

作　　者：陈鼎[1] 张贤春[1] 陈漠水[2] 

机构地区：[1]海口市人民医院海港分院综合科,海南海口570311 [2]海口市人民医院心内科,海南海口570311

出　　处：《贵阳医学院学报》2015年第8期873-875,共3页Journal of Guiyang Medical College

摘　　要：目的:观察氨氯地平阿托伐他汀钙片在高血压合并冠心病治疗效果。方法:收集92例高血压合并冠心病患者,根据不同治疗方案将患者分为对照组和实验组,对照组采用硝苯地平缓释片治疗,实验组采用实氨氯地平阿托伐他汀钙片治疗,比较两组血压、总胆固醇、甘油三酯等指标,观察两组的治疗效果。结果:两组治疗前的收缩压与舒张压比较均无统计学意义(P>0.05);治疗后,实验组的收缩压与舒张压均显著低于对照组(P<0.05),治疗后的血压均明显下降,与治疗前比较差异有统计学意义(P<0.05);实验组总有效率为95.65%,对照组总有效率为82.61%(P<0.05);实验组TC、TG、LDL-L、HDL-L指标显著低于对照组(P<0.05)。结论:高血压合并冠心病应用氨氯地平阿托伐他汀钙片治疗的疗效确切。Objective：To investigate the clinical effect of amlodipine atorvastatin calcium tablet on Patients with hypertension with coronary heart disease（ CHD）. Methods：A total of 92 cases of hyper-tension patients with coronary heart disease（ CHD）were were divided into control group and experi-mental group. The control group treated with nifedipine zyban,experimental group treated with solid amlodipine atorvastatin calcium tablet. Comaring indexes of blood pressure,total cholesterol and tri-glyceride. Results：The systolic and diastolic blood pressure of two groups before treatment showed no statistical significance（P﹥0. 05）. After treatment,systolic and diastolic blood pressure of experimen-tal group were significantly lower than control group（ P﹤0 . 05 ）. The experimental group total effec-tive rate was 95. 65%;the control group total effective rate was 82. 61%（P﹤0. 05）;TC,TG,LDL-L,HDL-L index of experimental group were lower than that of control group significantly（P﹤0. 05）. Conclusion：Amlodipine atorvastatin calcium tablet is effective for patients with hypertension with cor-onary heart disease.

关 键 词：高血压 冠心病 氨氯地平 阿托伐他汀 疗效 

分 类 号：R544.1[医药卫生—心血管疾病] R541.4[医药卫生—内科学]