抗菌药物专项整治活动前后北京大学深圳医院抗菌药物应用分析  

Analysis of Perioperative Antibiotic Use in Peking University Shenzhen Hospital before and after The Special Rectification

作　　者：徐仿周[1] 肖平[2] 何光明[1] 宋琳[3] 

机构地区：[1]北京大学深圳医院药学部,广东深圳518036 [2]北京大学深圳医院院长办公室,广东深圳518036 [3]北京大学深圳医院药物临床试验机构办公室,广东深圳518036

出　　处：《中国医院用药评价与分析》2015年第5期652-655,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解北京大学深圳医院(以下简称"我院")在开展抗菌药物专项整治活动中的具体管理措施以及所取得的成效,探讨如何对抗菌药物的不合理应用进行有效干预,以进一步促进抗菌药物的临床合理应用。方法:调取我院信息系统(HIS系统)中2011—2014年抗菌药物的销售及使用数据,结合2011-2014年我院门诊及住院诊疗人次数据,统计我院抗菌药物专项整治活动前、专项整治活动后以及持续改进后抗菌药物合理应用指标的变化,对我院抗菌药物临床专项整治活动效果进行分析及评价。结果:专项整治活动后,门诊抗菌药物的使用比例持续下降至12.24%,抗菌药物处方所占比例处于较低水平;抗菌药物使用强度也有了很大的改善,从专项整治活动前的76.06 DDD/(100人·d)下降至专项整治活动后的42.2 DDD/(100人·d);各项抗菌药物使用指标都有了很大改善,说明当前我院对于抗菌药物的管理措施是卓有成效的。讨论:在抗菌药物的专项整治方面,我院除应进一步完善抗菌药物临床应用管理相关制度和指标外,还需加强全院及临床科室范围内抗菌药物合理应用知识的培训,不断提升医师合理应用抗菌药物的意识,还可借鉴国外较为先进的医院感染控制措施,从内涵技术和外在形式上促进抗菌药物在我院的合理使用。OBJECTIVE：ABTRACT To investigate the management measures taken in Peking University Shenzhen Hospital （ hereinafter referred to as “our hospital”） during special rectification on antibiotic use and the outcomes achieved, and discuss how to achieve effective intervention on the irrational antibiotic use so as to promote clinical rational use of antibiotics.METHODS：Based on the consumption data of antibiotics during 2011-2014 period retrieved from Hospital Information System plus the data such as the number of outpatients and inpatients, the antibiotic use in our hospital before and after implementation of Special Rectification Activities on Clinical Antibiotic Use were analyzed meanwhile the outcome of the Special Rectification Activities were evaluated.RESULTS：The rate of antibiotic use in the outpatients decreased continuously to 12.24%and the proportion of antibiotic prescriptions in the total was on the lower side;the AUD （ antibiotic use density） improved greatly, down from 76.06 DDD/（100 persons per day） to 42.2 DDD/（100 persons per day）;all the antibiotic use indicators have been improved greatly, achiving satisfactory outcome on antiobiotic use.CONCLUSIONS： In special rectification activities on antibiotic use, it is important to further improve the systems and indicators on the clinical use of antibotics, strengthen training in clinical departments about the rational use of antibiotics, enhance physicians＇awareness on antibiotic use, take the advanced management measures on hospital infection control taken abroad as reference to promote rational use of antibotics in our hospital both in connotation technology and in form.

关 键 词：抗菌药物专项整治 管理措施 分级管理 用药分析 

分 类 号：R978.1[医药卫生—药品]