常规用药联合药学服务治疗高血压病的临床观察  

Routine Treatment plus Pharmaceutical Care for Patients with Hypertension: Clincal Observation

作　　者：李晓兰[1] 

机构地区：[1]焦作市第二人民医院药学部,河南焦作454001

出　　处：《中国医院用药评价与分析》2015年第6期835-838,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨河南省焦作市第二人民医院(以下简称"我院")临床药师参与高血压病治疗的方法和效果。方法:将我院心血管内科2013年3月—8月住院的高血压患者120例随机分为实验组和对照组,每组60例。对照组只接受常规治疗,实验组在常规治疗基础上联合药学服务,即临床药师参与对患者在药物遴选、服药依从性、给药时段性、联合药物治疗、不良反应的防范及生活方式的干预等方面的服务,对存在合并疾病者给予相应治疗。临床药师对实验组患者出院后电话随访3个月,收集2组患者入院前和出院时的肾功能、血脂指标及入院前、后心律及血压变化情况。结果:2组患者入院前肾功能、血脂指标均不在正常范围内,2组比较差异均无统计学意义(P>0.05),出院时2组患者肾功能、三酰甘油、低密度脂蛋白较入院前明显好转,与入院前比较差异均具有统计学意义(P<0.05);实验组治疗后收缩压、舒张压均低于治疗前,差异均具有统计学意义(P<0.05)。3个月后复查,2组患者收缩压、舒张压、三酰甘油、高密度脂蛋白、低密度脂蛋白比较差异均具有统计学意义(P<0.05),实验组结果明显优于对照组。结论:临床药师参与高血压病治疗,能充分为患者提供专业性服务,降低高血压病并发症的发生率。OBJECTIVE：To explore the approach for clinical pharmacist to participate in the treatment of patients with hypertension and evaluate its effectiveness.METHODS：A total of 120 patients with hypertension hospitalized in our hospital from March to August in 2013 were randomized to either experimental group or control group, of 60 cases each.The control group received routine treatment alone, while the experimental group received routine treatment plus pharmaceutical care.The pharmaceutical care provided by pharmacists included interventions on drug selection, patients＇compliance to medication, time of medication, drug combination, prevention of adverse reactions and intervention on lifestyle.The patients with complications were given corresponding treatment.The patients in the experimental group after discharge from hospital were followed-up by clinical pharmacists for 3 months.The rengal function, blood lipid indexes, cardiac rhythm and blood pressure before admission and on discharge were recorded. RESULTS：The rengal function and blood lipid indexes of the two groups were not within normal limits, showing no statistically significant differences between the two groups （P〉0.05）;on discharge, the renal function, triglyceride, low density lipoprotein in the two groups of patients were significantly improved as compared with before admission, showing statistically significant difference （ P 〈0.05 ）; after treatment, systolic blood pressure and diastolic blood pressure were lower than before treatment, and the differences were statistically significant （P〈0.05）.At 3 months of follow-up, the differences between the two groups in systolic blood pressure, diastolic blood pressure, triglyceride, high density lipoprotein and low density lipoprotein were statistically significant （ P 〈0.05 or P 〈0.01 ） , with the experimental group showing better improvement than in the control group.CONCLUSIONS： Clinical pharmacists involved in the treatment of patient with hypertension can give full play

关 键 词：高血压病 药剂师 肾功能试验 血压 药物疗法 血脂 

分 类 号：R544.1[医药卫生—心血管疾病] R972[医药卫生—内科学]