未足月胎膜早破期待治疗时间的影响因素及意义  

The influencing factors of latency period and its clinical importances in premature prelabor rupture of membranes

作　　者：郑亮慧 陈素清[1] 刘照贞[1] 林琳[1] 潘地灵 

机构地区：[1]福州福建省妇幼保健院妇产科,350501

出　　处：《中国妇产科临床杂志》2015年第4期329-332,共4页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的探讨未足月胎膜早破（PPROM）期待治疗时间的影响因素及临床意义。方法回顾性分析2011年12月至2013年1月在福建省妇幼保健院分娩的28-33周＋6未足月胎膜早破92例患者的临床资料。根据期待治疗时间将其分为48-168h组（52例）和〉168h组（40例）。比较两组患者孕周、羊水量、白细胞计数、C反应蛋白（CRP）水平及新生儿并发症等。结果 48-168h组患者的年龄和破膜孕周分别为（30.87±5.45）岁和（31.19±1.53）周,〉168h组分别为（28.18±4.60）岁和（30.32±1.56）周,两组比较,差异均有统计学意义（P均〈0.05）;48-168h组新生儿窒息和低出生体质量儿发生率分别为19.23%（10/52）和57.69%（30/52）,〉168h组分别为5.00%（2/40）和80.00%（32/40）,两组比较,差异均有统计学意义（P均〈0.05）;孕妇年龄、破膜孕周与期待治疗时间呈负相关[OR值分别为0.364（95%CI：0.146-0.913）和0.673（95%CI：0.496-0.915）],羊水指数与期待治疗时间呈正相关[OR值=1.258（95%CI：1.034-1.531）]。结论未足月胎膜早破期待治疗时间与孕妇年龄、破膜孕周及羊水指数有关。期待治疗时间长新生儿窒息发生率低,低出生体质量儿发生率高。Objective To study the influencing factors of latency period and its clinical importances in premature prelabor rupture of membranes（PPROM）.Methods Ninety two PPROM pregnant women who delivered at the 28-33＋6 week of pregnancy in Fujian Provincial Maternity and Child Care Center from December 2011 to January 2013 were recruited in this study.Patients were devided into two groups according to latency period,the latency time in group 1was 48-168h（52samples）and in group 2was〉168h（40samples）.Parameters of age,gestational weeks,amniotic fluid volume,white blood cell count,c-reaction protein,newborns＇ complications were compared between the two groups.Results Patients＇ age and gestational weeks of PPROM in the group 1were（30.87±5.45）years and（31.19±1.53）weeks,which were（28.18±4.60）years and（30.32±1.56）weeks in group2,the difference was significant（P〈0.05）.The rate of neonatal asphyxia rate and underweight newborns in group 1were 19.23%（10/52）and 57.69%（30/52）,which were 5.00%（2/40）and 80.00%（32/40）in group2.The difference was statistically significant（P〈0.05）.Patients＇ age,gestational weeks of PPROM were negatively related to latency period [OR=0.364（95%CI：0.146-0.913）and 0.673（95%CI：0.496-0.915）],amniotic fluid volume was positively related to latency period[OR=1.258（95%CI：1.034-1.531）].ConclusionsThe latency period of PPROM is related to patients＇ age,gestational weeks of PPROM and amniotic fluid volume.The longer the latency period is,the lower the asphyxia rates of newborns is,and the higher the rate of underweight newborns is.

关 键 词：胎膜早破 期待治疗时间 羊水过少 新生儿 妊娠结局 

分 类 号：R714.433[医药卫生—妇产科学]