培美曲塞维持治疗晚期非小细胞肺癌的不良反应观察及护理  

Side effects of pemetrexed in the maintenance therapy of nonsmall-cell lung cancer at advanced stage and the nursing measures

作　　者：韦汝琼[1] 李高华[1] 卢晓[1] 凌国珍[1] 

机构地区：[1]广西医科大学附属肿瘤医院化疗二科,广西南宁530021

出　　处：《现代临床护理》2015年第5期48-50,共3页Modern Clinical Nursing

摘　　要：目的探讨培美曲塞维持治疗晚期非小细胞肺癌的不良反应观察和总结护理方法。方法观察培美曲塞维持治疗晚期非小细胞肺癌的51例患者的不良反应,并采取相应的护理措施。结果本组51例患者发生的不良反应主要为骨髓抑制、胃肠道反应、皮疹。其中骨髓抑制33例、胃肠道反应14例、皮疹4例,不良反应程度均为Ⅰ-Ⅱ度,经积极对症处理和护理后均得到缓解。结论做好心理护理、不良反应观察及护理和出院指导,是顺利完成培美曲塞维持治疗晚期非小细胞肺癌治疗的主要措施。Objective To explore the side effects of pemetrexed in the maintenane therapy of nonsmall-cell lung cancer（NSCLC）at advanced stage and summarize the nursing measures. Methods Fifty-one NSCLC patients were treated maintenance therapy by pemetrexed. The side effects were observed and corresponding nursing measures were taken. Results The side effects included bone marrow depression of 33 cases, adverse reactions in gastrointestinal tract of 14 cases, and skin rashes of 4 cases, all at the degree of III. All of them were alleviated after active treatments. Conclusion Such nursing measures as close of side effects and careful nursing to the NSCLC patients treated with maintenance therapy with temetrexed are main measures for the success of treatment.

关 键 词：培美曲塞 非小细胞肺癌 护理 

分 类 号：R473.73[医药卫生—护理学]