短效胰岛素联合格列苯脲治疗糖尿病的临床效果  

Clinical Effect of Short Acting Insulin Combined with Glibenclamidetreat-ment of Diabetes

作　　者：徐媛[1] 

机构地区：[1]新汶矿业集团公司协庄煤矿医院药剂科,山东新泰271221

出　　处：《糖尿病新世界》2015年第13期17-18,共2页Diabetes New World Magazine

摘　　要：目的探讨短效胰岛素联合格列苯脲治疗糖尿病的临床效果。方法选择2010年1月—2013年12月该院收治的2型糖尿病患者100例,按照随机数字法分为两组,各50例,对照组使用短效胰岛素400u皮下注射,1次/d,观察组使用短效胰岛素联合格列美脲治疗,两组均连续治疗6月,比较两组治疗后血糖控制情况,以及治疗过程中发生的并发症。结果观察组治疗后空腹血糖、餐后2小时血糖及随机血糖均显著低于对照组,差异有统计学意义(P<0.05),观察组发生高血糖、低血糖及酮症酸中毒的比例显著低于对照组,差异有统计学意义(P<0.05)。结论联合使用短效胰岛素与格列美脲,能较好的控制患者血糖,减少治疗期间并发症,值得临床重视。Objective To explore the clinical effect of short acting insulin combined With glibenclamide treatment of diabetes. Methods 100 cases were selected and randomly divided into two groups, each of 50 cases,the control group was taken short acting insulin subcutaneous injection of 400u, 1 times a day, the observation group use short effect insulin combined with glimepiride treatment, two groups were treated for June,compared with two groups after treatment, blood sugar control,occurrence and treatment process complications. Results the observationgroup after treatment, fasting blood glucose, postprandial 2 hour blood glucose and random blood glucose levels were significantly lower than those of the control group （P〈0.05）, the observation group occurredhy- perglycemia, hypoglycemia and ketoacidosis rates were significantlylower than that of the control group （P〈0.05）. Conclusion the combineduse of short acting insulin with glimepiride to glycemic control in patients with better, reduce complications during treat- ment, worthy of clinicalimportance.

关 键 词：短效胰岛素 格列苯脲 糖尿病 

分 类 号：R714.256[医药卫生—妇产科学]