胱抑素C和β_2微球蛋白在2型糖尿病早期肾损害诊断中的意义  

Cystatin C and β_2-microglobulin in Type 2 Diabetes Early Diagnosis of Kidney Damage

作　　者：王益芳[1] 戴洪波[1] 欧秋娟[1] 欧阳慧[1] 

机构地区：[1]湖南省湘南学院附属医院肾内科,湖南郴州423400

出　　处：《糖尿病新世界》2015年第13期41-42,共2页Diabetes New World Magazine

摘　　要：目的分析胱抑素C和β2微球蛋白在2型糖尿病早期肾损害诊断中的意义。方法选择该院2014年1月—2015年1月收治的2型糖尿病患者100例,并选择同期健康体检者80例,对全部入选者的胱抑素C(Cysc)、β2微球蛋白(β2-MG)、尿素(Urea)、肌酐(Crea)进行检测,并对检测结果进行对比分析。结果糖尿病患者的胱抑素C和β2微球蛋白显著高于健康体检者,比较差异有统计学意义(P<0.05),而且在患者病情发展中胱抑素C和β2微球蛋白水平不断增高。结论在2型糖尿病早期肾损害诊断中,胱抑素C和β2微球蛋白具有非常重要的临床应用价值和参考价值。Objective To analyze the eystatin C and β2-microglobulin significance in the diagnosis of type 2 diabetes in early nephropathy. Methods Select 100 cases of type 2 diabetes in our hospital from January 2014 to January 2015 were treated and choose healthy 80 cases over the same period, for all the selected candidates of cystatin C, v2-microglobulin, urea, creatinine de- tection , and the test results were analyzed. Results Diabetes cystatin C and β2-microg]obulin was significantly higher than healthy controls, the difference was statistically significant（P〈0.05）, and in patients with disease progression in cystatin C and β2-mi- croglobulin level continues increased. Conclusion Early diagnosis of diabetic nephropathy in type 2, and cystatin C and β2 mi- croglobulin has very important clinical value and reference value.

关 键 词：胱抑素C Β2微球蛋白 2型糖尿病 早期肾损害 诊断 意义 

分 类 号：R587[医药卫生—内分泌]