PC-MRI对三脑室底造瘘术后脑脊液循环的研究  

To Study Cerebrospinal Fluid Flow Of Post Endoscopic Third Ventriculostomy By PCMRI

作　　者：方翠敬 雷益[2] 林帆[2] 

机构地区：[1]广东省东莞康华医院神经内科,广东东莞523000 [2]深圳大学第一附属医院(深圳市第二人民医院)放射科,广东深圳518000

出　　处：《中国CT和MRI杂志》2015年第8期14-16,共3页Chinese Journal of CT and MRI

摘　　要：目的通过相位对比磁共振电影成像技术观察第三脑室底造瘘术瘘口区脑脊液流动动力学情况,并与正常人中脑导水管脑脊液流动情况作对比,从而评估手术疗效。方法使用Siemens Avanto 1.5T MR对30例正常人及12例行三脑室底造瘘术患者分别行导水管及造瘘口PC-MRI扫描,利用Argus软件进行数据测量及分析,测量其在一个心动周期内脑脊液流动的各参数,如峰值流速、平均流速、净流量、平均流速率等。结果 30例正常人中脑导水管脑脊液流动各数值(收缩期峰值流速、舒张期峰值流速、净流量)与12例造瘘术后瘘管区脑脊液流动相关参数进行独立t检验,P值均大于0.05。结论第三脑室底造瘘口脑脊液流动形式与正常人相似,呈周期搏动样流动。心脏收缩期脑脊液从瘘管口上端流向下端,舒张期脑脊液从瘘管口下端流向上端。造瘘术可重建脑脊液循环通道,使之达到正常中脑导水管的生理特点。Objective Objective To study and analyze cerebrospinal fluid（CSF） flow in patients with endoscopic third ventriculostomy（ETV） compared with volunteers, to assess the surgery efficacy by investigating. Methods 30 volunteers and 12 patients with endoscopic third ventriculostomy were selected. CSF flow was measure inside the cerebral aqueduct and the stoma area separately with cine PC（Siemens Avanto 1.5T） in all case. All diffusiontensor data（Systolic Velocity、Average Velocity、Net Flows、Average Flow Rate） were processed with Argus software on workstation. Results Independent t test was processed on PSV、DSV and NF between normal and ventriculostomy and found that P0.05 in all three tests. Conclusions The CSF flow pattern in patients performed with ventriculostomy in the floor of the third ventricle is similar with the normal, presenting as bidirectional periodical pulsating waves in the fistula. The cerebrospinal fluid circulation can be rebuilt by ETV, so that its normal physiological requirements can be satisfied. CSF flow waveforms analysis by MR cine PC seems to be a reliable, reproducible, and sensitive method for assessing the CSF dynamics.

关 键 词：磁共振成像 相位对比 脑脊液流动 中脑导水管 第三脑室底造瘘术 

分 类 号：R445.2[医药卫生—影像医学与核医学]