尿镉的硝酸石墨炉原子吸收光谱测定方法研究  

Determination of urinary cadmium by GFAAS with matrix modifier of HNO_3

作　　者：麦剑平[1] 刘移民[1,2] 

机构地区：[1]广州市职业病防治院,广东广州510620 [2]中山大学公共卫生学院,广东广州510080

出　　处：《职业卫生与应急救援》2015年第3期198-200,共3页Occupational Health and Emergency Rescue

基　　金：广东省自筹经费类科技计划项目;广东省医学科研基金(编号:A2014597);广东省"十二五"医学重点专科(编号:粤卫函[2012]20号);广州市医学重点学科建设项目(编号:穗卫科[2013]21号);广州市职业环境与健康效应实验室建设项目(编号:2014SY000020);广州市民生科技重大项目(编号:2012Y2-00029-1);广州市"121人才梯队工程"后备人才项目;广州市卫生局市医药卫生科技项目(编号:20131A011099)

摘　　要：目的仅使用硝酸作为基体改进剂,建立一种使用石墨炉原子吸收光谱仪,简便、快速、准确地直接测定尿中镉浓度的方法。方法使用热电MKⅡ-M6原子吸收分光光度计,以0.1%硝酸溶液作为基体改进剂,运用适当的升温程序,对尿镉进行测定。结果浓度在0~10.0μg/L范围内,尿镉浓度和吸光度具有良好的线性关系;最低检测浓度为0.05μg/L;重现性试验相对标准差（RSD）为1.91%~2.84%;试验回收率为98.3%~101.6%。结论使用0.1%硝酸溶液作为基体改进剂,应用热电MKⅡ-M6原子吸收分光光度计直接测定尿镉,是一种简单、快速、准确、环保且易于普及推广的方法 。Objective To develop a simple,rapid and accurate method for direct determination of cadmium in urine with GFAAS by using HNO3 as an appropriate matrix modifier. Methods Using 0.1% HNO3 as matrix modifier with proper temperature programming,the cadmium in urine was determined by MK Ⅱ M6 graphite furnace atomic absorption spectrometry. Results The c urve had a good linearity in the range of 0- 10 μg/L. The detection limit was 0.05 μg/L,the RSD from 1.91%- 2.84%,and the recovery rate from 98.3% to 101.6%. Conclusion Using 0.1% HNO3 as matrix modifier, direct determination of the cadmium in urine by MKⅡ M6 graphite furnace atomic absorption spectrometry becomes simple,rapid,accurate,environmental and user-friendly.

关 键 词：尿镉 石墨炉原子吸收光谱法 基体改进剂 硝酸溶液 

分 类 号：R115[医药卫生—公共卫生与预防医学] R446