经皮椎体后凸成形术配合唑来膦酸治疗骨质疏松性胸腰椎骨折的疗效分析  

Efficacy of percutaneous kyphoplasty combined with aclasta in treatment of osteoporotic thoracolumbar fractures

作　　者：刘沛[1] 陈思思[1] 肖少雄[1] 

机构地区：[1]武汉市第一医院脊柱创伤骨科,湖北省武汉市430022

出　　处：《实用老年医学》2015年第6期494-496,共3页Practical Geriatrics

摘　　要：目的探讨经皮椎体后凸成形术（PKP）配合唑来膦酸（密固达）药物治疗骨质疏松性胸腰椎骨折的疗效。方法 2008年12月至2013年12月,收集我院行PKP配合密固达药物治疗的骨质疏松性胸腰椎骨折的95例老年患者的临床资料及随访资料,随访时间2-60月,平均32.4月。分别使用Oswestry功能障碍指数（ODI）和视觉模拟评分法（VAS）对术前和术后临床疗效进行评价。结果手术时间为20-85 min（平均29 min）,术中累计X线透视时间平均32 s,术中出血量为5-10 ml（平均7.5 ml）,平均住院6 d,均在术后1-2 d佩戴腰围下床。术前第1天及术后1月随访ODI及VAS评分结果均有显著性差异（P〈0.05）。结论 PKP配合密固达药物治疗骨质疏松性胸腰椎骨折创伤小、疗效肯定,可有效改善老年患者症状和预防患者再发骨折。Objective To investigate the efficacy of percutaneous kyphoplasty（ PKP） combined with aclasta in the treatment of osteoporotic thoracolumbar fractures. Methods From December 2008 to December 2013,the clinical data and follow-up data of 95 elderly patients with osteoporotic thoracolumbar receiving PKP and aclasta were selected and observed. All the cases were followed up for 2-60 months（ average 32. 4 months）. Oswestry disability index（ ODI） and visual analogue scale（ VAS） were applied to evaluate the clinical efficacy of preoperative and postoperative. Results The time of operation was 20-85 min（ average 29 min）,the mean time of cumulative intraoperative fluoroscopy time was 32 s,the amount of bleeding in operation was 5-10 ml（ average 7. 5 ml）,and the average length of hospital stay was 6 d. All patients got off the bed wearing waist after operation. There was significant difference in ODI and score of VAS between preoperative and postoperative（ P〈0. 05）. Conclusions PKP combined with aclasta in treatment of osteoporotic thoracolumbar fractures is effective with mild hurt,and can improve symptoms and prevention of recurrent fracture in elderly patients.

关 键 词：椎体后凸成形术 唑来膦酸 骨质疏松 胸腰椎骨折 

分 类 号：R683.2[医药卫生—骨科学]