超声造影在甲状腺微小实性结节良恶性鉴别诊断中的价值  

Value of contrast-enhanced ultrasound in differential diagnosis of benign and malignant thyroid micro solid nodules

作　　者：李晨[1] 郝玉芝[2] 王勇[1] 秦川[1] 杨裕辉[1] 高光旭 

机构地区：[1]新疆克拉玛依市中心医院超声科,834000 [2]中国医学科学院肿瘤医院超声科

出　　处：《临床超声医学杂志》2015年第7期453-456,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨超声造影对甲状腺微小实性结节良恶性鉴别诊断的价值。方法回顾分析113例(126个结节)经手术病理证实的甲状腺微小实性结节患者的超声造影特征,评估其诊断的敏感性、特异性、准确性、阳性预测值、阴性预测值及约登指数。结果 126个微小实性结节中,恶性结节74个(58.7%),良性结节52个(41.3%)。74个甲状腺微小恶性结节超声造影特征多表现为:向心性(67.5%)、不均匀性(83.8%)、低增强(82.4%)、慢进同出(66.1%)、周边等增强(93.2%),超声造影诊断甲状腺微小恶性结节的敏感性、特异性、准确性、阳性预测值、阴性预测值、约登指数分别为62.2%、96.2%、76.2%、95.8%、64.1%、58.4%;52个甲状腺微小良性结节超声造影多表现为周边环状高增强(63.5%)。结论超声造影对甲状腺微小实性结节的良恶性鉴别诊断有较高的应用价值。Objective To investigate the value of contrast-enhanced ultrasound（CEUS） in differential diagnosis of benign and malignant thyroid micro solid nodules.Methods The ultrasonic characteristics of 126 thyroid micro solid nodules in113 patients confirmed by operations and pathology were analyzed retrospectively,and the sensitivity,specificity,accuracy,Youden＇s index,positive predictive value and negative predictive value were evaluated.Results In the 126 micro solid nodules,there were 74 malignant nodules（58.7%） and 52 benign nodules（41.3%）.The CEUS features of malignant nodules showed：centrality（67.5%）,heterogeneity（83.8%）,hypoenhancement（82.4%）,slow in and simultaneous out（66.1%）,peripheral isoenhancement（93.2%）,the sensitivity,specificity,accuracy,positive predictive value,negative predictive value and Youden＇s index in diagnosis were 62.2%,96.2%,76.2%,95.8%,64.1% and 58.4%.The CEUS features of benign nodules showed peripheral ring hyperenhancement（63.5%） Conclusion CEUS has high value in differential diagnosis of benign and malignant thyroid micro solid nodules.

关 键 词：超声检查 造影剂 甲状腺微小实性结节 良恶性 

分 类 号：R445.1[医药卫生—影像医学与核医学]